Id |
Subject |
Object |
Predicate |
Lexical cue |
T146 |
0-43 |
Sentence |
denotes |
SARS-CoV-2 Spike Glycoprotein Gene Analysis |
T147 |
45-82 |
Sentence |
denotes |
Sequence percent similarity analysis. |
T148 |
83-259 |
Sentence |
denotes |
We assessed the nucleotide percent similarity using the MegAlign software program, where the similarity between the novel SARS-CoV-2 isolates was in the range of 99.4% to 100%. |
T149 |
260-447 |
Sentence |
denotes |
Among the other Serbecovirus CoV sequences, the novel SARS-CoV-2 sequences revealed the highest similarity to bat-SL-CoV, with nucleotide percent identity ranges between 88.12 and 89.65%. |
T150 |
448-556 |
Sentence |
denotes |
Meanwhile, earlier reported SARS-CoVs showed 70.6 to 74.9% similarity to SARS-CoV-2 at the nucleotide level. |
T151 |
557-769 |
Sentence |
denotes |
Further, the nucleotide percent similarity was 55.4%, 45.5% to 47.9%, 46.2% to 46.6%, and 45.0% to 46.3% to the other four subgenera, namely, Hibecovirus, Nobecovirus, Merbecovirus, and Embecovirus, respectively. |
T152 |
770-930 |
Sentence |
denotes |
The percent similarity index of current outbreak isolates indicates a close relationship between SARS-CoV-2 isolates and bat-SL-CoV, indicating a common origin. |
T153 |
931-1221 |
Sentence |
denotes |
However, particular pieces of evidence based on further complete genomic analysis of current isolates are necessary to draw any conclusions, although it was ascertained that the current novel SARS-CoV-2 isolates belong to the subgenus Sarbecovirus in the diverse range of betacoronaviruses. |
T154 |
1222-1372 |
Sentence |
denotes |
Their possible ancestor was hypothesized to be from bat CoV strains, wherein bats might have played a crucial role in harboring this class of viruses. |
T155 |
1374-1404 |
Sentence |
denotes |
SplitsTree phylogeny analysis. |
T156 |
1405-1566 |
Sentence |
denotes |
In the unrooted phylogenetic tree of different betacoronaviruses based on the S protein, virus sequences from different subgenera grouped into separate clusters. |
T157 |
1567-1692 |
Sentence |
denotes |
SARS-CoV-2 sequences from Wuhan and other countries exhibited a close relationship and appeared in a single cluster (Fig. 1). |
T158 |
1693-1874 |
Sentence |
denotes |
The CoVs from the subgenus Sarbecovirus appeared jointly in SplitsTree and divided into three subclusters, namely, SARS-CoV-2, bat-SARS-like-CoV (bat-SL-CoV), and SARS-CoV (Fig. 1). |
T159 |
1875-2140 |
Sentence |
denotes |
In the case of other subgenera, like Merbecovirus, all of the sequences grouped in a single cluster, whereas in Embecovirus, different species, comprised of canine respiratory CoVs, bovine CoVs, equine CoVs, and human CoV strain (OC43), grouped in a common cluster. |
T160 |
2141-2289 |
Sentence |
denotes |
Isolates in the subgenera Nobecovorus and Hibecovirus were found to be placed separately away from other reported SARS-CoVs but shared a bat origin. |