PMC:7405836 / 125295-136990 JSONTXT 10 Projects

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Id Subject Object Predicate Lexical cue
T841 0-35 Sentence denotes PREVENTION, CONTROL, AND MANAGEMENT
T842 36-180 Sentence denotes In contrast to their response to the 2002 SARS outbreak, China has shown immense political openness in reporting the COVID-19 outbreak promptly.
T843 181-336 Sentence denotes They have also performed rapid sequencing of COVID-19 at multiple levels and shared the findings globally within days of identifying the novel virus (225).
T844 337-421 Sentence denotes The move made by China opened a new chapter in global health security and diplomacy.
T845 422-658 Sentence denotes Even though complete lockdown was declared following the COVID-19 outbreak in Wuhan, the large-scale movement of people has resulted in a radiating spread of infections in the surrounding provinces as well as to several other countries.
T846 659-740 Sentence denotes Large-scale screening programs might help us to control the spread of this virus.
T847 741-846 Sentence denotes However, this is both challenging as well as time-consuming due to the present extent of infection (226).
T848 847-1012 Sentence denotes The current scenario demands effective implementation of vigorous prevention and control strategies owing to the prospect of COVID-19 for nosocomial infections (68).
T849 1013-1165 Sentence denotes Follow-ups of infected patients by telephone on day 7 and day 14 are advised to avoid any further unintentional spread or nosocomial transmission (312).
T850 1166-1349 Sentence denotes The availability of public data sets provided by independent analytical teams will act as robust evidence that would guide us in designing interventions against the COVID-19 outbreak.
T851 1350-1455 Sentence denotes Newspaper reports and social media can be used to analyze and reconstruct the progression of an outbreak.
T852 1456-1552 Sentence denotes They can help us to obtain detailed patient-level data in the early stages of an outbreak (227).
T853 1553-1707 Sentence denotes Immediate travel restrictions imposed by several countries might have contributed significantly to preventing the spread of SARS-CoV-2 globally (89, 228).
T854 1708-1890 Sentence denotes Following the outbreak, a temporary ban was imposed on the wildlife trade, keeping in mind the possible role played by wild animal species in the origin of SARS-CoV-2/COVID-19 (147).
T855 1891-2080 Sentence denotes Making a permanent and bold decision on the trade of wild animal species is necessary to prevent the possibility of virus spread and initiation of an outbreak due to zoonotic spillover (1).
T856 2081-2207 Sentence denotes Personal protective equipment (PPE), like face masks, will help to prevent the spread of respiratory infections like COVID-19.
T857 2208-2394 Sentence denotes Face masks not only protect from infectious aerosols but also prevent the transmission of disease to other susceptible individuals while traveling through public transport systems (313).
T858 2395-2513 Sentence denotes Another critical practice that can reduce the transmission of respiratory diseases is the maintenance of hand hygiene.
T859 2514-2674 Sentence denotes However, the efficacy of this practice in reducing the transmission of respiratory viruses like SARS-CoV-2 is much dependent upon the size of droplets produced.
T860 2675-2800 Sentence denotes Hand hygiene will reduce disease transmission only if the virus is transmitted through the formation of large droplets (314).
T861 2801-3026 Sentence denotes Hence, it is better not to overemphasize that hand hygiene will prevent the transmission of SARS-CoV-2, since it may produce a false sense of safety among the general public that further contributes to the spread of COVID-19.
T862 3027-3252 Sentence denotes Even though airborne spread has not been reported in SARS-CoV-2 infection, transmission can occur through droplets and fomites, especially when there is close, unprotected contact between infected and susceptible individuals.
T863 3253-3479 Sentence denotes Hence, hand hygiene is equally as important as the use of appropriate PPE, like face masks, to break the transmission cycle of the virus; both hand hygiene and face masks help to lessen the risk of COVID-19 transmission (315).
T864 3480-3569 Sentence denotes Medical staff are in the group of individuals most at risk of getting COVID-19 infection.
T865 3570-3633 Sentence denotes This is because they are exposed directly to infected patients.
T866 3634-3834 Sentence denotes Hence, proper training must be given to all hospital staff on methods of prevention and protection so that they become competent enough to protect themselves and others from this deadly disease (316).
T867 3835-3988 Sentence denotes As a preventive measure, health care workers caring for infected patients should take extreme precautions against both contact and airborne transmission.
T868 3989-4126 Sentence denotes They should use PPE such as face masks (N95 or FFP3), eye protection (goggles), gowns, and gloves to nullify the risk of infection (299).
T869 4127-4240 Sentence denotes The human-to-human transmission reported in SARS-CoV-2 infection occurs mainly through droplet or direct contact.
T870 4241-4410 Sentence denotes Due to this finding, frontline health care workers should follow stringent infection control and preventive measures, such as the use of PPE, to prevent infection (110).
T871 4411-4644 Sentence denotes The mental health of the medical/health workers who are involved in the COVID-19 outbreak is of great importance, because the strain on their mental well-being will affect their attention, concentration, and decision-making capacity.
T872 4645-4772 Sentence denotes Hence, for control of the COVID-19 outbreak, rapid steps should be taken to protect the mental health of medical workers (229).
T873 4773-4964 Sentence denotes Since the living mammals sold in the wet market are suspected to be the intermediate host of SARS-CoV-2, there is a need for strengthening the regulatory mechanism for wild animal trade (13).
T874 4965-5120 Sentence denotes The total number of COVID-19 confirmed cases is on a continuous rise and the cure rate is relatively low, making disease control very difficult to achieve.
T875 5121-5248 Sentence denotes The Chinese government is making continuous efforts to contain the disease by taking emergency control and prevention measures.
T876 5249-5432 Sentence denotes They have already built a hospital for patients affected by this virus and are currently building several more for accommodating the continuously increasing infected population (230).
T877 5433-5647 Sentence denotes The effective control of SARS-CoV-2/COVID-19 requires high-level interventions like intensive contact tracing, as well as the quarantine of people with suspected infection and the isolation of infected individuals.
T878 5648-5787 Sentence denotes The implementation of rigorous control and preventive measures together might control the R0 number and reduce the transmission risk (228).
T879 5788-5989 Sentence denotes Considering the zoonotic links associated with SARS-CoV-2, the One Health approach may play a vital role in the prevention and control measures being followed to restrain this pandemic virus (317–319).
T880 5990-6182 Sentence denotes The substantial importation of COVID-19 presymptomatic cases from Wuhan has resulted in independent, self-sustaining outbreaks across major cities both within the country and across the globe.
T881 6183-6267 Sentence denotes The majority of Chinese cities are now facing localized outbreaks of COVID-19 (231).
T882 6268-6375 Sentence denotes Hence, deploying efficient public health interventions might help to cut the spread of this virus globally.
T883 6376-6514 Sentence denotes The occurrence of COVID-19 infection on several cruise ships gave us a preliminary idea regarding the transmission pattern of the disease.
T884 6515-6637 Sentence denotes Cruise ships act as a closed environment and provide an ideal setting for the occurrence of respiratory disease outbreaks.
T885 6638-6800 Sentence denotes Such a situation poses a significant threat to travelers, since people from different countries are on board, which favors the introduction of the pathogen (320).
T886 6801-7048 Sentence denotes Although nearly 30 cruise ships from different countries have been found harboring COVID-19 infection, the major cruise ships that were involved in the COVID-19 outbreaks are the Diamond Princess, Grand Princess, Celebrity Apex, and Ruby Princess.
T887 7049-7120 Sentence denotes The number of confirmed COVID-19 cases around the world is on the rise.
T888 7121-7272 Sentence denotes The success of preventive measures put forward by every country is mainly dependent upon their ability to anticipate the approaching waves of patients.
T889 7273-7390 Sentence denotes This will help to properly prepare the health care workers and increase the intensive care unit (ICU) capacity (321).
T890 7391-7650 Sentence denotes Instead of entirely relying on lockdown protocols, countries should focus mainly on alternative intervention strategies, such as large-scale testing, contract tracing, and localized quarantine of suspected cases for limiting the spread of this pandemic virus.
T891 7651-7770 Sentence denotes Such intervention strategies will be useful either at the beginning of the pandemic or after lockdown relaxation (322).
T892 7771-7906 Sentence denotes Lockdown should be imposed only to slow down disease progression among the population so that the health care system is not overloaded.
T893 7907-8070 Sentence denotes The reproduction number (R0) of COVID-19 infection was earlier estimated to be in the range of 1.4 to 2.5 (70); recently, it was estimated to be 2.24 to 3.58 (76).
T894 8071-8240 Sentence denotes Compared to its coronavirus predecessors, COVID-19 has an R0 value that is greater than that of MERS (R0 < 1) (108) but less than that of SARS (R0 value of 2 to 5) (93).
T895 8241-8401 Sentence denotes Still, to prevent further spread of disease at mass gatherings, functions remain canceled in the affected cities, and persons are asked to work from home (232).
T896 8402-8634 Sentence denotes Hence, it is a relief that the current outbreak of COVID-19 infection can be brought under control with the adoption of strategic preventive and control measures along with the early isolation of subsequent cases in the coming days.
T897 8635-8876 Sentence denotes Studies also report that since air traffic between China and African countries increased many times over in the decade after the SARS outbreak, African countries need to be vigilant to prevent the spread of novel coronavirus in Africa (225).
T898 8877-8948 Sentence denotes Due to fear of virus spread, Wuhan City was completely shut down (233).
T899 8949-9177 Sentence denotes The immediate control of the ongoing COVID-19 outbreaks appears a mammoth task, especially for developing countries, due to their inability to allocate quarantine stations that could screen infected individuals’ movements (234).
T900 9178-9493 Sentence denotes Such underdeveloped countries should divert their resources and energy to enforcing the primary level of preventive measures, like controlling the entry of individuals from China or countries where the disease has flared up, isolating the infected individuals, and quarantining individuals with suspected infection.
T901 9494-9614 Sentence denotes Most of the sub-Saharan African countries have a fragile health system that can be crippled in the event of an outbreak.
T902 9615-9790 Sentence denotes Effective management of COVID-19 would be difficult for low-income countries due to their inability to respond rapidly due to the lack of an efficient health care system (65).
T903 9791-9935 Sentence denotes Controlling the imported cases is critical in preventing the spread of COVID-19 to other countries that have not reported the disease until now.
T904 9936-10058 Sentence denotes The possibility of an imported case of COVID-19 leading to sustained human-to-human transmission was estimated to be 0.41.
T905 10059-10255 Sentence denotes This can be reduced to a value of 0.012 by decreasing the mean time from the onset of symptoms to hospitalization and can only be made possible by using intense disease surveillance systems (235).
T906 10256-10442 Sentence denotes The silent importations of infected individuals (before the manifestation of clinical signs) also contributed significantly to the spread of disease across the major cities of the world.
T907 10443-10654 Sentence denotes Even though the travel ban was implemented in Wuhan (89), infected persons who traveled out of the city just before the imposition of the ban might have remained undetected and resulted in local outbreaks (236).
T908 10655-10803 Sentence denotes Emerging novel diseases like COVID-19 are difficult to contain within the country of origin, since globalization has led to a world without borders.
T909 10804-10928 Sentence denotes Hence, international collaboration plays a vital role in preventing the further spread of this virus across the globe (237).
T910 10929-11013 Sentence denotes We also predict the possibility of another outbreak, as predicted by Fan et al. (6).
T911 11014-11088 Sentence denotes Indeed, the present outbreak caused by SARS-CoV-2 (COVID-19) was expected.
T912 11089-11172 Sentence denotes Similar to previous outbreaks, the current outbreak also will be contained shortly.
T913 11173-11340 Sentence denotes However, the real issue is how we are planning to counter the next zoonotic CoV epidemic that is likely to occur within the next 5 to 10 years or even sooner (Fig. 7).
T914 11341-11368 Sentence denotes FIG 7 Coronavirus origins.
T915 11369-11517 Sentence denotes Coronavirus is the most prominent example of an emerging virus that has crossed the species barrier from wild animals to humans, like SARS and MERS.
T916 11518-11600 Sentence denotes The origin of SARS-CoV-2 is also suspected to be from an intermediate animal host.
T917 11601-11695 Sentence denotes The possibility of crossing the species barrier again for the fourth time cannot be ruled out.