PMC:7405836 / 114358-115442 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T777 0-265 Sentence denotes Appropriate RBD-specific MAbs can be recognized by a relative analysis of RBD of SARS-CoV-2 to that of SARS-CoV, and cross-neutralizing SARS-CoV RBD-specific MAbs could be explored for their effectiveness against COVID-19 and further need to be assessed clinically.
T778 266-378 Sentence denotes The U.S. biotechnology company Regeneron is attempting to recognize potent and specific MAbs to combat COVID-19.
T779 379-529 Sentence denotes An ideal therapeutic option suggested for SARS-CoV-2 (COVID-19) is the combination therapy comprised of MAbs and the drug remdesivir (COVID-19) (201).
T780 530-685 Sentence denotes The SARS-CoV-specific human MAb CR3022 is found to bind with SARS-CoV-2 RBD, indicating its potential as a therapeutic agent in the management of COVID-19.
T781 686-821 Sentence denotes It can be used alone or in combination with other effective neutralizing antibodies for the treatment and prevention of COVID-19 (202).
T782 822-1084 Sentence denotes Furthermore, SARS-CoV-specific neutralizing antibodies, like m396 and CR3014, failed to bind the S protein of SARS-CoV-2, indicating that a particular level of similarity is mandatory between the RBDs of SARS-CoV and SARS-CoV-2 for the cross-reactivity to occur.