PMC:7405836 / 106990-107876 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T731 0-159 Sentence denotes Several therapeutic agents, such as lopinavir/ritonavir, chloroquine, and hydroxychloroquine, have been proposed for the clinical management of COVID-19 (299).
T732 160-492 Sentence denotes A molecular docking study, conducted in the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2 using different commercially available antipolymerase drugs, identified that drugs such as ribavirin, remdesivir, galidesivir, tenofovir, and sofosbuvir bind RdRp tightly, indicating their vast potential to be used against COVID-19 (305).
T733 493-721 Sentence denotes A broad-spectrum antiviral drug that was developed in the United States, tilorone dihydrochloride (tilorone), was previously found to possess potent antiviral activity against MERS, Marburg, Ebola, and Chikungunya viruses (306).
T734 722-806 Sentence denotes Even though it had broad-spectrum activity, it was neglected for an extended period.
T735 807-886 Sentence denotes Tilorone is another antiviral drug that might have activity against SARS-CoV-2.