LitCovid-sentences  

PMC:7405836 / 101241-103785 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T697 0-93 Sentence denotes COVID-19 patients showing severe signs are treated symptomatically along with oxygen therapy.
T698 94-243 Sentence denotes In such cases where the patients progress toward respiratory failure and become refractory to oxygen therapy, mechanical ventilation is necessitated.
T699 244-341 Sentence denotes The COVID-19-induced septic shock can be managed by providing adequate hemodynamic support (299).
T700 342-455 Sentence denotes Several classes of drugs are currently being evaluated for their potential therapeutic action against SARS-CoV-2.
T701 456-757 Sentence denotes Therapeutic agents that have anti-SARS-CoV-2 activity can be broadly classified into three categories: drugs that block virus entry into the host cell, drugs that block viral replication as well as its survival within the host cell, and drugs that attenuate the exaggerated host immune response (300).
T702 758-842 Sentence denotes An inflammatory cytokine storm is commonly seen in critically ill COVID-19 patients.
T703 843-918 Sentence denotes Hence, they may benefit from the use of timely anti-inflammation treatment.
T704 919-1137 Sentence denotes Anti-inflammatory therapy using drugs like glucocorticoids, cytokine inhibitors, JAK inhibitors, and chloroquine/hydroxychloroquine should be done only after analyzing the risk/benefit ratio in COVID-19 patients (301).
T705 1138-1275 Sentence denotes There have not been any studies concerning the application of nonsteroidal anti-inflammatory drugs (NSAID) to COVID-19-infected patients.
T706 1276-1420 Sentence denotes However, reasonable pieces of evidence are available that link NSAID uses with the occurrence of respiratory and cardiovascular adverse effects.
T707 1421-1560 Sentence denotes Hence, as a cautionary approach, it is better to recommend the use of NSAIDs as the first-line option for managing COVID-19 symptoms (302).
T708 1561-1691 Sentence denotes The use of corticosteroids in COVID-19 patients is still a matter of controversy and requires further systematic clinical studies.
T709 1692-1855 Sentence denotes The guidelines that were put forward to manage critically ill adults suggest the use of systemic corticosteroids in mechanically ventilated adults with ARDS (303).
T710 1856-2017 Sentence denotes The generalized use of corticosteroids is not indicated in COVID-19, since there are some concerns associated with the use of corticosteroids in viral pneumonia.
T711 2018-2196 Sentence denotes Stem cell therapy using mesenchymal stem cells (MSCs) is another hopeful strategy that can be used in clinical cases of COVID-19 owing to its potential immunomodulatory capacity.
T712 2197-2346 Sentence denotes It may have a beneficial role in attenuating the cytokine storm that is observed in severe cases of SARS-CoV-2 infection, thereby reducing mortality.
T713 2347-2544 Sentence denotes Among the different types of MSCs, expanded umbilical cord MSCs can be considered a potential therapeutic agent that requires further validation for managing critically ill COVID-19 patients (304).