| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T432 |
0-173 |
Sentence |
denotes |
Due to the heterogeneity of clinical and flow cytometric data, non-parametric tests of association were preferentially used throughout this study unless otherwise specified. |
| T433 |
174-456 |
Sentence |
denotes |
Correlation coefficients between ordered features (including discrete ordinal, continuous scale, or a mixture of the two) were quantified by the Spearman rank correlation coefficient and significance was assessed by the corresponding non-parametric methods (null hypothesis: ρ = 0). |
| T434 |
457-657 |
Sentence |
denotes |
Tests of association between mixed continuous versus non-ordered categorical variables were performed by unpaired Wilcoxon test (for n = 2 categories) or by Kruskal-Wallis test (for n > 2 categories). |
| T435 |
658-734 |
Sentence |
denotes |
Association between categorical variables was assessed by Fisher-exact test. |
| T436 |
735-936 |
Sentence |
denotes |
For association testing illustrated in heatmaps, categorical variables with more than 2 categories (e.g., ABO blood type) were transformed into binary dummy variables for each category versus the rest. |
| T437 |
937-1051 |
Sentence |
denotes |
All tests were performed two-sided, using a nominal significance threshold of P < 0.05 unless otherwise specified. |
| T438 |
1052-1244 |
Sentence |
denotes |
When appropriate to adjust for multiple hypothesis testing, false discovery rate (FDR) correction was performed using the Benjamini-Hochberg procedure at the FDR < 0.05 significance threshold. |
| T439 |
1245-1534 |
Sentence |
denotes |
Joint statistical modeling to adjust for confounding of demographic factors (age, sex, and race) when testing for association of UMAP Components 1 and 2 with the NIH Ordinal Severity Scale was performed using ordinal logistic regression provided by the polr function of the R package MASS. |
| T440 |
1535-1617 |
Sentence |
denotes |
Statistical analysis of flow cytometry data was performed using R package rstatix. |
| T441 |
1618-1709 |
Sentence |
denotes |
Other details, if any, for each experiment are provided within the relevant figure legends. |
