PMC:7402624 / 61496-63456 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T356 0-48 Sentence denotes Patients, subjects, and clinical data collection
T357 49-235 Sentence denotes Patients admitted to the Hospital of the University of Pennsylvania with a positive SARS-CoV2 PCR test were screened and approached for informed consent within 3 days of hospitalization.
T358 236-339 Sentence denotes Healthy donors (HD) were adults with no prior diagnosis of or recent symptoms consistent with COVID-19.
T359 340-430 Sentence denotes Normal reference ranges for HDs were the UPenn clinical laboratory values shaded in green.
T360 431-601 Sentence denotes Recovered COVID-19 subjects (RD) were adults with a prior positive COVID-19 PCR test by self-report who met the definition of recovery by the Centers for Disease Control.
T361 602-766 Sentence denotes HD and RD were recruited initially by word of mouth and subsequently through a centralized University of Pennsylvania resource website for COVID-19-related studies.
T362 767-816 Sentence denotes Peripheral blood was collected from all subjects.
T363 817-934 Sentence denotes For inpatients, clinical data were abstracted from the electronic medical record into standardized case report forms.
T364 935-1100 Sentence denotes ARDS was categorized in accordance with the Berlin definition reflecting each subject’s worst oxygenation level and with physician adjudication of chest radiographs.
T365 1101-1280 Sentence denotes APACHE III scoring was based on data collected in the first 24 hours of ICU admission or the first 24 hours of hospital admission for subjects admitted to general inpatient units.
T366 1281-1373 Sentence denotes Clinical laboratory data were abstracted from the date closest to research blood collection.
T367 1374-1418 Sentence denotes HD and RD completed a survey about symptoms.
T368 1419-1528 Sentence denotes After enrollment, the clinical team determined three patients to be COVID-negative and/or PCR false positive.
T369 1529-1583 Sentence denotes Two of these patients were classified as Immunotype 3.
T370 1584-1667 Sentence denotes In keeping with inclusion criteria, these subjects were maintained in the analysis.
T371 1668-1786 Sentence denotes The statistical significance reported in Fig. 6K did not change when analysis was repeated without the three patients.
T372 1787-1960 Sentence denotes All participants or their surrogates provided informed consent in accordance with protocols approved by the regional ethical research boards and the Declaration of Helsinki.