| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T246 |
0-94 |
Sentence |
denotes |
(A) NIH ordinal scale for COVID-19 clinical severity. (B) Frequencies of major immune subsets. |
| T247 |
95-588 |
Sentence |
denotes |
Significance determined by unpaired Wilcoxon test with BH correction: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001. (C) Heatmap of indicated immune parameters by row; donor type, disease severity, and mortality indicated across top. (D) UMAP projection of aggregated flow cytometry data. (E) Transformed UMAP projection; density contours drawn separately for healthy donor (HD), recovered donor (RD), and COVID-19 subjects (see Methods). (F) Bars represent mean of UMAP Component 1. |
| T248 |
589-787 |
Sentence |
denotes |
Dots represent individual subjects; bars shaded by subject group and/or severity score. (G) Density contour plots indicating variation of specified immune features across UMAP Component coordinates. |
| T249 |
788-909 |
Sentence |
denotes |
Relative expression (according to heat scale) shown for both individual patients (points) and overall density (contours). |
| T250 |
910-1587 |
Sentence |
denotes |
Spearman’s Rank Correlation coefficient (ρ) and p-value for each feature vs. Component 1 (C1) and Component 2 (C2) shown. (H) (Left) Spearman correlation between UMAP Components 1 and 2 and FlowSOM clusters. (Right) Select FlowSOM clusters and their protein expression. (I) Spearman correlation between UMAP Components 1 and 2 and clinical metadata. (J) Heatmap of immune parameters used to define Immunotype 3 indicated by row; disease severity and mortality indicated across top. (K) (Left) Transformed UMAP projection; patient status for Immunotype 3 indicated by color. (Right) Spearman correlation between Immunotype 3 and disease severity, mortality, and UMAP Components. |
