PMC:7396557 / 83148-86228 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T621 0-24 Sentence denotes Clinical Research on SFI
T622 25-223 Sentence denotes SFI is composed of Panax ginseng C.A.Mey. and Aconitum carmichaeli Debeaux, and has properties that include enhancing cardiac function, increasing blood pressure, and protecting ischemic myocardium.
T623 224-377 Sentence denotes It is widely used to rescue from shock (infectious or cardiogenic shock) caused by various reasons, cardiac failure, and arrhythmia in clinical practice.
T624 378-472 Sentence denotes Recent studies have shown that SFI significantly protects against lung injury (see Table 3 ).
T625 473-718 Sentence denotes SFI has been recommended in China’s SARS Diagnosis and Treatment Scheme (Version 2004), the MERS Diagnosis and Treatment Scheme (Version 2015), and the Diagnosis and Treatment Scheme for Human Infections with H7N9 Avian Influenza (Version 2017).
T626 719-866 Sentence denotes Qiu Z.L. et al. observed a therapeutic effect of SFI in patients with severe sepsis and an impact on the expression levels of serum IL-6 and IL-10.
T627 867-1080 Sentence denotes They found that SFI significantly lowered IL-6 levels in patients with severe sepsis and regulated the balance between pro- and anti-inflammatory factors, thus, improving the therapeutic effect (Qiu et al., 2012).
T628 1081-1198 Sentence denotes Ning Zhang et al. randomized 160 patients with sepsis into an SFI treatment group and a conventional treatment group.
T629 1199-1325 Sentence denotes By collecting post-treatment immunological parameters, they conducted a comparative analysis of the impact on immune function.
T630 1326-1495 Sentence denotes The results showed that patients in the SFI treatment group had increased CD4+ and CD8+ T cell counts in peripheral blood and upregulated HLA-DR expression in monocytes.
T631 1496-1641 Sentence denotes In addition, the SFI treatment group had a better response than the control group for duration of vasopressor administration and APACHE-II score.
T632 1642-1824 Sentence denotes The results showed that SFI enhanced cellular immune function in patients with septic shock and might become an important adjunctive therapy for sepsis patients (Zhang et al., 2017).
T633 1825-1928 Sentence denotes Another study found that SFI played an active role in the treatment of severe pneumonia in the elderly.
T634 1929-2216 Sentence denotes Among 89 elderly patients with severe pneumonia, the SFI treatment group had significantly decreased levels of TNF-α, IL-6, and IL-8 7 days after administration, indicating that SFI effectively reduced inflammatory mediators, thus, playing an active therapeutic effect (Lv et al., 2017).
T635 2217-2534 Sentence denotes Min Ma et al. conducted clinical research on 80 patients with traumatic acute lung injury, and found that SFI significantly improved respiratory rate, improved the oxygen index, and reduced levels of intracellular adhesion molecule 1 (ICAM-1), endothelin-1 (ET-1), and NO, thus, improving prognosis of these patients.
T636 2535-2629 Sentence denotes This study provided a potential new therapy for traumatic acute lung injury (Ma et al., 2019).
T637 2630-2758 Sentence denotes Jie Li et al. observed an impact of SFI intervention on duration of mechanical ventilation in patients with respiratory failure.
T638 2759-2866 Sentence denotes The results showed that the total response rate in the SFI group was higher than that of the control group.
T639 2867-3080 Sentence denotes SFI significantly improved serum prealbumin and high-sensitivity CRP levels in patients with respiratory failure and improved their oxygen index, thus, shortening the duration of mechanical ventilation (Li, 2013).