PMC:7396557 / 2296-11026 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T18 0-12 Sentence denotes Introduction
T19 13-67 Sentence denotes COVID-19 is an emerging and rapidly evolving epidemic.
T20 68-221 Sentence denotes The cumulative number of confirmed cases globally reached 1,040,772 on April 4, 2020, comprising 149,790 (14.39%) cured cases, and 55,698 (5.35%) deaths.
T21 222-307 Sentence denotes The causative organism has been designated as the 2019 novel coronavirus (2019-nCoV).
T22 308-472 Sentence denotes On January 30, 2020, the epidemic was declared a public health emergency of international concern by the World Health Organization (WHO) (Fisher and Heymann, 2020).
T23 473-785 Sentence denotes On February 11, 2020, the WHO Director-General, Tedros Adhanom Ghebreyesus, announced that the disease caused by this new coronavirus was “COVID-19,” which is an acronym for “coronavirus disease 2019.” The virus seems to be highly contagious and had quickly spread to 119 countries and regions by March 12, 2020.
T24 786-1163 Sentence denotes The clinical spectrum of COVID-19 varies from asymptomatic or paucisymptomatic forms to clinical symptoms characterized by respiratory failure that necessitates mechanical ventilation and support in an intensive care unit (ICU), to multiorgan and systemic manifestations in terms of sepsis, septic shock, and multiple organ dysfunction syndromes (MODS) (Wu and McGoogan, 2020).
T25 1164-1294 Sentence denotes Currently, there is no effective anti-coronaviral drug that is recommended for treatment of COVID-19, and no vaccine is available.
T26 1295-1438 Sentence denotes There is no evidence supporting the efficacy of broad-spectrum antibiotics, gamma globulin, interferon, or corticosteroid therapy for COVID-19.
T27 1439-1553 Sentence denotes Treatment is symptomatic, and oxygen therapy represents the major intervention for patients with severe infection.
T28 1554-1696 Sentence denotes Mechanical ventilation may be necessary in cases of respiratory failure refractory to oxygen therapy (Huang et al., 2020; Zhang et al., 2020).
T29 1697-1845 Sentence denotes Traditional Chinese Medicine (TCM) has a long history and has played an important role in the prevention and treatment of serious epidemic diseases.
T30 1846-2045 Sentence denotes During the development of the COVID-19 epidemic, more than 3,100 TCM medical staff were deployed to Hubei province, and TCM was included in the guidelines for the diagnosis and treatment of COVID-19.
T31 2046-2139 Sentence denotes Currently, the total number of confirmed cases treated by TCM has reached 60,107 (Gao, 2020).
T32 2140-2287 Sentence denotes The decoctions, CPMs, acupuncture, and other TCM treatments have been comprehensively used for treatment, mainly based on syndrome differentiation.
T33 2288-2511 Sentence denotes Specific CPMs have been widely employed to treat COVID-19 with remarkable therapeutic effects (National Health Commission of the People’s Republic of China and National Administration of Traditional Chinese Medicine, 2020).
T34 2512-2704 Sentence denotes CPMs are approved by the National Drug Regulatory Authority of China and processed according to prescribed methods using Chinese herbal medicines as raw materials, guided by the theory of TCM.
T35 2705-2804 Sentence denotes They are available in different dosage forms, such as pill, tablet, capsule, granule, or injection.
T36 2805-2902 Sentence denotes The use of CPMs is guided by syndrome differentiation and overall analysis of signs and symptoms.
T37 2903-3031 Sentence denotes Provinces of China have prepared therapeutic schedules for the treatment of COVID-19 based on actual conditions (see Table 1 ).
T38 3032-3124 Sentence denotes Many guidelines and expert consensus in China have recommended using CPMs to treat COVID-19.
T39 3125-3213 Sentence denotes In this article, we identify the top 10 recommended CPMs to treat COVID-19 ( Figure 1 ).
T40 3214-3537 Sentence denotes The list of CPMs includes Huoxiang Zhengqi capsule (HXZQC), Lianhua Qingwen capsule (LHQWC), Jinhua Qinggan granule (JHQGG), Shufeng Jiedu capsule (SFJDC), Tanreqing injection (TRQI), Xiyanping injection (XYPI), Xuebijing injection (XBJI), Shenfu injection (SFI), Shengmai injection (SMI), and Angong Niuhuang pill (AGNHP).
T41 3538-3728 Sentence denotes Information on the drugs include the recommended guidelines, drug ingredients, indications, pharmacological research, clinical research, usage and dosage, adverse reactions, and precautions.
T42 3729-3781 Sentence denotes Table 1 Therapeutic regimens for COVID-19 in China.
T43 3782-3792 Sentence denotes Serial No.
T44 3794-3849 Sentence denotes Therapeutic regimen of COVID-19 Website Date of issue
T45 3850-3914 Sentence denotes 1 National Health Commission of the People’s Republic of China.
T46 3915-4071 Sentence denotes Guideline on Diagnosis and Treatment of COVID-19 (Trial 7th edition) http://www.nhc.gov.cn/yzygj/s7653p/202003/46c9294a7dfe4cef80dc7f5912eb1989.shtml Mar.
T47 4072-4080 Sentence denotes 03, 2020
T48 4081-4238 Sentence denotes 2 Beijing Municipal COVID-19 TCM Preventive and Therapeutic Regime (Trial Version IV) http://zyj.beijing.gov.cn/sy/tzgg/202003/t20200307_1682382.html Mar.
T49 4239-4247 Sentence denotes 06, 2020
T50 4248-4396 Sentence denotes 3 Tianjin Municipal COVID-19 TCM Preventive and Therapeutic Regime (Trial Version III) http://wsjk.tj.gov.cn/art/2020/2/21/art_70_71264.html Feb.
T51 4397-4405 Sentence denotes 20, 2020
T52 4406-4533 Sentence denotes 4 Hebei Provincial COVID-19 TCM Therapeutic regime (Trial Version IV) https://mp.weixin.qq.com/s/9QTqGDw6vkQyWX-VrjulqQ Feb.
T53 4534-4542 Sentence denotes 13, 2020
T54 4543-4716 Sentence denotes 5 Gansu Provincial TCM Preventive and Therapeutic Regime of Novel Coronavirus Infected Pneumonia (Trial Version II) http://wsjk.gansu.gov.cn/file.jsp?contentId=83488 Feb.
T55 4717-4725 Sentence denotes 01, 2020
T56 4726-4866 Sentence denotes 6 Guangdong Provincial COVID-19 TCM Therapeutic Regime (Trial Version II) http://szyyj.gd.gov.cn/zwgk/gsgg/content/post_2902010.html Feb.
T57 4867-4875 Sentence denotes 18, 2020
T58 4876-5045 Sentence denotes 7 Shaanxi Provincial TCM Therapeutic Regime of Novel Coronavirus Infected Pneumonia (Trial Version II) http://sxwjw.shaanxi.gov.cn/art/2020/2/2/art_10_67602.html Feb.
T59 5046-5054 Sentence denotes 02, 2020
T60 5055-5245 Sentence denotes 8 Hunan Provincial TCM Diagnosis And Treatment Scheme of Novel Coronavirus Infected Pneumonia (Trial Version III) http://tcm.hunan.gov.cn/tcm/xxgk/tzgg/202002/t20200203_11168981.html Feb.
T61 5246-5254 Sentence denotes 03, 2020
T62 5255-5425 Sentence denotes 9 Jilin Provincial TCM Therapeutic Regime of Novel Coronavirus Infected Pneumonia (Trial Version I) http://jltcm.jl.gov.cn/tzgg/xgdt/202001/t20200126_6654768.html Jan.
T63 5426-5434 Sentence denotes 26, 2020
T64 5435-5614 Sentence denotes 10 Technical Guidelines of Sichuan Province on TCM Prevention and Control of COVID-19 http://wsjkw.sc.gov.cn/scwsjkw/zcwj11/2020/2/6/ac6fea21a3ad490aa0a73c9d70004ad6.shtml Feb.
T65 5615-5623 Sentence denotes 05, 2020
T66 5624-5793 Sentence denotes 11 Shanghai Municipal COVID-19 TCM Diagnosis And Treatment Scheme (Trial Version II) http://wsjkw.sh.gov.cn/zyygz2/20200224/a1f1aab9745e4490867cb4aaf40eaad0.html Feb.
T67 5794-5802 Sentence denotes 24, 2020
T68 5803-5952 Sentence denotes 12 Jiangxi Provincial COVID-19 TCM Preventive and Therapeutic Regime (Trial Version III) http://www.jxhfpc.gov.cn/doc/2020/02/21/140518.shtml Feb.
T69 5953-5960 Sentence denotes 21,2020
T70 5961-6130 Sentence denotes 13 COVID-19 TCM Therapeutic Regime of Guangxi Zhuang Autonomous Region (Trial Version III) http://wsjkw.gxzf.gov.cn/zwgk/zfxxgkml/wsjszh/zyzy/2020/0224/1752.html Feb.
T71 6131-6139 Sentence denotes 24, 2020
T72 6140-6314 Sentence denotes 14 TCM Preventive and Therapeutic Regime for Novel Coronavirus Infected Pneumonia of the Xinjiang Uygur Autonomous Region http://www.xjhfpc.gov.cn/info/2074/17765.htm Jan.
T73 6315-6323 Sentence denotes 30, 2020
T74 6324-6494 Sentence denotes 15 Hainan Provincial COVID-19 TCM Preventive and Therapeutic Regime (Trial Version III) http://wst.hainan.gov.cn/swjw/xxgk/0200/0202/202003/t20200305_2756534.html Feb.
T75 6495-6503 Sentence denotes 14, 2020
T76 6504-6649 Sentence denotes 16 Heilongjiang Provincial COVID-19 TCM Preventive and Therapeutic Regime (Version III) http://www.hljdaily.com.cn/article/90/154485.html Feb.
T77 6650-6658 Sentence denotes 26, 2020
T78 6659-6826 Sentence denotes 17 Guizhou Provincial COVID-19 TCM Preventive and Therapeutic Reference Regime (Version II) http://atcm.guizhou.gov.cn/xwzx/zyyw/202002/t20200219_50116162.html Feb.
T79 6827-6835 Sentence denotes 19, 2020
T80 6836-7027 Sentence denotes 18 Shanxi Provincial of TCM Preventive and Therapeutic Regime of Novel Coronavirus Infected Pneumonia (For Trial Implementation) http://www.sx.chinanews.com/news/2020/0201/162758.html Feb.
T81 7028-7036 Sentence denotes 01, 2020
T82 7037-7180 Sentence denotes 19 Jiangsu Provincial COVID-19 TCM Diagnosis and Intervention Regime (Trial Version III) http://www.jstcm.com/article_info.asp?id=10042 Feb.
T83 7181-7189 Sentence denotes 18, 2020
T84 7190-7350 Sentence denotes 20 COVID-19 TCM Diagnosis and Treatment Scheme of the Nei Monggol Autonomous Region (Trial Version II) http://wjw.nmg.gov.cn/doc/2020/02/18/292482.shtml Feb.
T85 7351-7358 Sentence denotes 14,2020
T86 7359-7556 Sentence denotes 21 Liaoning Provincial TCM Diagnosis and Treatment Scheme of Novel Coronavirus Infected Pneumonia (Trial Version II) http://wsjk.ln.gov.cn/wst_zdzt/xxgzbd/tzgg/202002/t20200203_3733244.html Feb.
T87 7557-7565 Sentence denotes 03, 2020
T88 7566-7676 Sentence denotes 22 Anhui Provincial COVID-19 TCM Therapist Consensus http://wjw.ah.gov.cn/ahtcm/NewsDetail.aspx?id=987 Feb.
T89 7677-7685 Sentence denotes 18, 2020
T90 7686-7874 Sentence denotes 23 Shandong Provincial TCM Diagnosis and Treatment Scheme of Novel Coronavirus Infected Pneumonia http://wsjkw.shandong.gov.cn/ztzl/rdzt/qlzhfkgz/fkdt/202002/t20200201_2513391.html Jan.
T91 7875-7883 Sentence denotes 31, 2020
T92 7884-8080 Sentence denotes 24 TCM Preventive and Therapeutic Regime for Novel Coronavirus Infected Pneumonia of the Ningxia Hui Autonomous Region (For Trial Implementation) http://wsjkw.nx.gov.cn/info/1040/13360.htm Jan.
T93 8081-8089 Sentence denotes 28, 2020
T94 8090-8336 Sentence denotes 25 TCM Diagnosis and Treatment Scheme and Preventive Scheme for Novel Coronavirus Infected Pneumonia of Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology https://www.tjh.com.cn/html/2020/0208/28991.shtml Feb.
T95 8337-8344 Sentence denotes 08,2020
T96 8345-8401 Sentence denotes Figure 1 The top 10 CPMs for the treatment of COVID-19:
T97 8402-8730 Sentence denotes 1) Huoxiang Zhengqi capsule (HXZQC), 2) Lianhua Qingwen capsule (LHQWC), 3) Jinhua Qinggan granule (JHQGG), 4) Shufeng Jiedu capsule (SFJDC), 5) Tanreqing injection (TRQI), 6) Xiyanping injection (XYPI), 7) Xuebijing injection (XBJI), 8) Shenfu injection (SFI), 9) Shengmai injection (SMI), and 10) Angong Niuhuang pill (AGNHP).