LitCovid-sentences  

PMC:7394275 / 17860-20076 JSONTXT 12 Projects

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Id Subject Object Predicate Lexical cue
T88 0-255 Sentence denotes COVID-19 patients with human immunodeficiency virus (HIV) infection accompanied by CD4 + T-lymphocyte count < 200 cells/μL, allo-HSCT, SOT, or other immune impaired are susceptible to cryptococcosis which predominantly present as meningoencephalitis [38].
T89 256-519 Sentence denotes Given the complexities surrounding the diagnosis of cryptococcosis and identification of Cryptococcus species including C. neoformans and C. gattii species, the diagnosis of cryptococcosis is usually based on a combination of clinical and laboratory confirmation.
T90 520-644 Sentence denotes The methods used to confirm the infection are culture, direct microscopy, histopathology, serology, and molecular detection.
T91 645-887 Sentence denotes To diagnose cryptococcosis, specimen from cerebrospinal fluid (CSF) can be mixed with India ink and observed under a microscope that the distinctive structure for Cryptococcus spp. with narrow budding encapsulated yeasts usually can be found.
T92 888-1015 Sentence denotes Samples for culture should be placed on Sabouraud dextrose agar at 30 °C for 7 days, in aerobic conditions, and observed daily.
T93 1016-1113 Sentence denotes Moreover, cultures from patients receiving systemic antifungal therapy might need longer to grow.
T94 1114-1161 Sentence denotes Cryptococcus appears as mucoid creamy colonies.
T95 1162-1299 Sentence denotes Capsular polysaccharides of Cryptococcus can be detected and quantified from body fluids such as serum, CSF, BAL, or pathological tissue.
T96 1300-1498 Sentence denotes Three formats of cryptococcal antigen (CrAg) detection tests are currently available: the latex agglutination test (LAT), the enzyme-linked immunoassay (EIA), and the lateral flow immunoassay (LFA).
T97 1499-1649 Sentence denotes These methods are rapid, sensitive, and specific, but have not been standardized for respiratory specimens such as BAL, pleural fluid, or sputum [32].
T98 1650-1803 Sentence denotes Molecular detection of Cryptococcus is required in specific situations where other diagnostic tools have failed to confirm a diagnosis of cryptococcosis.
T99 1804-1963 Sentence denotes These molecular methods include pan-fungal PCR, DNA sequencing for identification, multiplex PCR, isothermal amplification method, and probe-based microarrays.
T100 1964-2122 Sentence denotes Once a diagnosis cryptococcosis is made, a lumbar puncture and cerebrospinal fluid (CSF) examination (including antigen) are recommended in all patients [39].
T101 2123-2216 Sentence denotes Cryptococcus can disseminate into the central nervous system causing cryptococcal meningitis.