
PMC:7386875 / 42150-42511 8 Projects
Annnotations
Id | Subject | Object | Predicate | Lexical cue |
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T136 | 0-361 | Sentence | denotes | Thrombin efficiently cleaves and activates PAR-1, -3, and -4.131,132 Thus, in addition to being a potent platelet agonist, thrombin also activates immune effector and endothelial cells.133,134 Indeed, thrombin-induced activation of leukocytes results in the production of several cytokines and growth factors while also upregulating leukocyte adhesive function. |