| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T29 |
0-182 |
Sentence |
denotes |
Location [ref.] Age years Sex IPA risk factors Radiology BAL culture TA culture BAL GM Serum GM Other diagnostics Onset days post-ICU EORTC status Mod AspICU status Treatment Outcome |
| T30 |
183-408 |
Sentence |
denotes |
Cologne, Germany [11] 62 F Ex-smoker, moderate COPD, inhaled steroids Ground-glass opacities, crazy paving, peripheral nodular consolidation A. fumigatus NR (+) >2.5 (-) BAL PCR A. fumigatus NR No host factor# Putative V Died |
| T31 |
409-567 |
Sentence |
denotes |
Cologne, Germany [11] 70 M Ex-smoker Ground-glass opacities, occasional nodules (-) NR (+) >2.5 (+) 0.7 BAL PCR A. fumigatus NR No host factor Putative I Died |
| T32 |
568-820 |
Sentence |
denotes |
Cologne, Germany [11] 54 M Diabetes, systemic corticosteroids0.4 mg·kg−1·day−1×13 days Ground-glass opacities, nodular infiltrates with cavities, air crescent sign (-) A. fumigatus (+) >2.5 (-) BAL PCR A. fumigatus NR No host factor Putative C, V Alive |
| T33 |
821-1089 |
Sentence |
denotes |
Cologne, Germany [11] 73 M Smoker, bullous emphysema, severe COPD, inhaled steroids Ground-glass opacities, occasional nodules, known bullous emphysema ND A. fumigatus ND (-) TA PCR A. fumigatus NR No host factor Putative only if TA considered equivalent to BAL V Died |
| T34 |
1090-1297 |
Sentence |
denotes |
Cologne, Germany [11] 54 F None Ground-glass opacities, crazy paving, central and peripheral consolidation, smaller nodular infiltrates ND (-) ND (+) 2.7, 1.3 TA PCR (-) NR No host factor Putative C, V Alive |
| T35 |
1298-1477 |
Sentence |
denotes |
Munich, Germany [18] 80 M Pulmonary fibrosis Typical signs for COVID-19 pneumonia but no specific signs for IPA A. fumigatus NR (+) >6 (+) 1.5 5 No host factor Putative L-AmB Died |
| T36 |
1478-1639 |
Sentence |
denotes |
Munich, Germany [18] 70 M None Typical signs for COVID-19 pneumonia but no specific signs for IPA A. fumigatus NR (+) >6 (-) 6 No host factor Putative L-AmB Died |
| T37 |
1640-1855 |
Sentence |
denotes |
Paris, France [19] 74 M Myelodysplastic syndrome NR ND A. fumigatus ND (-) x2 TA PCR A. fumigatus x2, TA GM (-)×1, BDG and serum PCR (-) x2 4 No host factor Putative only if TA considered equivalent to BAL None Died |
| T38 |
1856-2091 |
Sentence |
denotes |
Paris, France [9] 53 M Dexamethasone 20 mg·day−1 days 1–5, 10 mg·day−1 days 6–10 Typical COVID-19 (-) NR (-) 0.89 (-) BAL PCR (-), Serum PCR (-), BDG (+) >500 NR No host factor Putative only if BAL GM cut-off lowered to >0.8 None Alive |
| T39 |
2092-2269 |
Sentence |
denotes |
Paris, France [9] 59 F Diabetes Typical COVID-19 A. fumigatus NR (-) (-) BAL PCR (-), serum PCR (-) NR No host factor Putative but note BAL culture (+) but BAL GM (-) None Alive |
| T40 |
2270-2512 |
Sentence |
denotes |
Paris, France [9] 69 F Dexamethasone 20 mg·day−1 days 1–5, 10 mg·day−1 days 6–10 Typical COVID-19 ND A. fumigatus ND (-) TA PCR A. fumigatus, serum PCR (-), BDG (-) NR No host factor Putative only if TA considered equivalent to BAL None Alive |
| T41 |
2513-2738 |
Sentence |
denotes |
Paris, France [9] 63 F Diabetes, dexamethasone 20 mg·day−1 days 1–5, 10 mg·day−1 days 6–10 Typical COVID-19 (-) NR (-) (+) 0.51 BAL PCR (-), BDG (+) 105 NR No host factor Putative but relies on serum GM of only 0.51 None Died |
| T42 |
2739-2940 |
Sentence |
denotes |
Paris, France [9] 43 M Asthma, corticosteroids Typical COVID-19 A. fumigatus NR (-) (-) BAL PCR (-), serum PCR (-), BDG (-) NR No host factor Putative but note BAL culture (+) but BAL GM (-) None Alive |
| T43 |
2941-3219 |
Sentence |
denotes |
Paris, France [9] 79 M Diabetes, Dexamethasone 20 mg·d−1 days 1–5, 10 mg·d−1 days 6–10 Typical COVID-19, segmental lung atelectasis A. fumigatus NR (-) (-) BAL PCR A. fumigatus, serum PCR (-), BDG (-) NR No host factor Putative but note BAL culture (+) but BAL GM (-) None Alive |
| T44 |
3220-3449 |
Sentence |
denotes |
Paris, France [9] 77 M Asthma, dexamethasone 20 mg·day−1 days 1–5, 10 mg·day−1 days 6–10 “Typical COVID-19”, emphysema A. fumigatus NR (+) 3.9 (-) BAL PCR A. fumigatus, serum PCR (-), BDG (+) 135 NR No host factor Putative V Died |
| T45 |
3450-3705 |
Sentence |
denotes |
Paris, France [9] 75 F Diabetes, dexamethasone 20 mg·day−1 days 1–5, 10 mg·day−1 days 6–10 Typical COVID-19 A. fumigatus NR (-) (-) BAL PCR, A. fumigatus, serum PCR (-), BDG (+) 450 NR No host factor Putative but note BAL culture (+) but BAL GM (-) C Died |
| T46 |
3706-3931 |
Sentence |
denotes |
Paris, France [9] 47 M Myeloma, corticosteroids Typical COVID-19, one peripheral nodule ND A. fumigatus ND (-) TA PCR A. fumigatus, serum PCR (-), BDG (-) NR Probable Putative only if TA considered equivalent to BAL None Died |
| T47 |
3932-4264 |
Sentence |
denotes |
Graz, Austria [20] 70 M Moderate COPD, steroid inhaler, obstructive sleep apnoea, diabetes Ground-glass opacities, crazy paving, reversed halo sign, progression of the bilateral infiltrates on day 2 chest radiography ND A. fumigatus ND (-) TA LFD (+), BDG (-) 3 No host factor Putative only if TA considered equivalent to BAL V Died |
| T48 |
4265-4394 |
Sentence |
denotes |
Antwerp, Belgium [8] 86 M None ND ND A. flavus ND (-) 9 No host factor Putative only if TA considered equivalent to BAL None Died |
| T49 |
4395-4517 |
Sentence |
denotes |
Antwerp, Belgium [8] 38 M None (+) A. fumigatus NR (+) >2.8 (-) Histology from bronchoscopy (+) 6 Proven Proven V, I Alive |
| T50 |
4518-4640 |
Sentence |
denotes |
Antwerp, Belgium [8] 62 M Diabetes ND A. fumigatus NR (+) >2.0 (-) Histology from bronchoscopy (+) 16 Proven Proven V Died |
| T51 |
4641-4763 |
Sentence |
denotes |
Antwerp, Belgium [8] 73 M Diabetes ND A. fumigatus NR (+) >2.8 (-) Histology from bronchoscopy (+) 5 Proven Proven V Alive |
| T52 |
4764-4936 |
Sentence |
denotes |
Antwerp, Belgium [8] 77 M Diabetes, chronic corticosteroids for pemphigus foliaceous ND A. fumigatus NR (+) 2.79 (-) Histology from bronchoscopy (+) 2 Proven Proven V Alive |
| T53 |
4937-5133 |
Sentence |
denotes |
Antwerp, Belgium [8] 55 M HIV (CD4 count >250, viral load <20) copies) ND (-) NR (-) (+) 0.8 Histology from bronchoscopy (-) 13 No host factor Putative but relies on serum GM of only 0.8 V, I Died |
| T54 |
5134-5241 |
Sentence |
denotes |
Antwerp, Belgium [8] 75 M AML with IPA 2012 ND A. fumigatus NR (+) 2.63 ND 8 No host factor Putative V Died |
| T55 |
5242-5491 |
Sentence |
denotes |
Breda, The Netherlands [10] 83 M Prednisolone 0.13 mg·kg−1·day−1×28 days for cardiomyopathy NR ND A. fumigatus ND (-) 3 Probable if steroid requirement reduced to <0.3 mg·kg−1·day−1 Putative only if TA considered equivalent to BAL V+A, or L-AmB Died |
| T56 |
5492-5710 |
Sentence |
denotes |
Breda, The Netherlands [10] 67 M Severe COPD, Post RT for NSCLC 2014, prednisolone 0.37 mg·kg−1·day−1×2 days NR ND A. fumigatus ND ND 3 No host factor Putative only if TA considered equivalent to BAL V+A, or L-AmB Died |
| T57 |
5711-5882 |
Sentence |
denotes |
Breda, The Netherlands [10] 75 M Moderate COPD NR A. fumigatus NR (+) 4.0 ND Mucoid white sputum left bronchus at bronchoscopy 5 No host factor Putative V+A, or L-AmB Died |
| T58 |
5883-5989 |
Sentence |
denotes |
Breda, The Netherlands [10] 43 M None NR (-) NR (+) 3.8 (-) 14 No host factor Putative V+A, or L-AmB Alive |
| T59 |
5990-6123 |
Sentence |
denotes |
Breda, The Netherlands [10] 57 M Asthma, inhaled steroids NR A. fumigatus NR (+) 1.6 (-) 5 No host factor Putative V+A, or L-AmB Died |
| T60 |
6124-6273 |
Sentence |
denotes |
Breda, The Netherlands [10] 58 M None NR ND A. fumigatus ND ND 28 No host factor Putative only if TA considered equivalent to BAL V+A, or L-AmB Alive |
| T61 |
6274-6480 |
Sentence |
denotes |
Paris, France [21] 80 M None Pleural effusions, alveolar condensation, ground-glass opacities, pulmonary cysts ND A. flavus ND ND NR No host factor Putative only if TA considered equivalent to BAL V, I Died |
| T62 |
6481-6692 |
Sentence |
denotes |
Milan, Italy [22] 73 M Diabetes Interstitial opacities with right upper lobe focal consolidation which progressively worsened A. fumigatus NR ND (+) 8.6 Lung histology from PM (+), PM tissue PCR Aspergillus spp. |
| T63 |
6693-6719 |
Sentence |
denotes |
9 Proven Proven L-AmB Died |
| T64 |
6720-6753 |
Sentence |
denotes |
Summary Median (IQR)70 (57–75) M: |
| T65 |
6754-7216 |
Sentence |
denotes |
26 (79%) out of 33 EORTC host factor: n=2 (6%); inhaled/systemic steroid exposure: n=16 (48%); diabetes: n=10 (30%); chronic lung disease: n=9 (27%) Nodules: n=6 (31.6%), cavity/halo-sign: n=2 (10.5%) 16 (72.7%) out of 22 with BAL 14 (66.7%) out of 21 with BAL GM 6 (21.4%) out of 28 with serum GM Median (IQR)5.5 (4.3–9) Proven: n=5; probable: n=1; no host factor: n=27 Proven: n=5; putative: n=11; putative with caveats: n=17 24 (72.7%) treated 21 (63.6%) died |
