LitCovid-sentences  

PMC:7376974 / 8240-9883 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T54 0-19 Sentence denotes Noble Nanoparticles
T55 20-200 Sentence denotes Noble nanoparticles (NPs), made of gold and silver, are attractive as antiviral agents for their surface functionalization versatility and their capacity to cleave disulfide bonds.
T56 201-287 Sentence denotes Their use in disinfection has been extensively studied for different types of viruses.
T57 288-444 Sentence denotes The morphology and the size of the NPs play a crucial role in their ability to efficiently interact with the capsids and in their toxicity for the organism.
T58 445-571 Sentence denotes These nanomaterials are characterized by a very large specific surface area (inversely proportional to the particle diameter).
T59 572-730 Sentence denotes As the particle size becomes smaller and smaller, the percentage of surface atoms increases, creating many unsaturated bonds due to lack of neighboring atoms.
T60 731-810 Sentence denotes As a consequence, AgNPs and AuNPs have unstable atoms with high surface energy.
T61 811-923 Sentence denotes This kind of structure provides a lot of contact adsorption sites and reaction points for further modifications.
T62 924-1029 Sentence denotes These chemical features allow to easily combine surface NP atoms with other atoms through chemical bonds.
T63 1030-1161 Sentence denotes Besides the composition of the metal core, several studies have pointed out the importance of the control of the surface chemistry.
T64 1162-1311 Sentence denotes The surface groups can: (1) stabilize NPs in the biological media, (2) insert targeting agents, and (3) enhance the circulation time inside the body.
T65 1312-1491 Sentence denotes Antiviral efficiency can be also enhanced by the multivalency effect, where highly branched ligands are used to locally augment the local concentration of the targeting molecules.
T66 1492-1643 Sentence denotes In this section the main strategies and results for silver (AgNPs) and gold (AuNPs) nanoparticles in blocking viral entry will be critically discussed.