PMC:7376974 / 81164-81715 8 Projects
Annnotations
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T502 | 0-448 | Sentence | denotes | Fullerenes also exhibit immunomodulation properties through the release of cytokines by bovine alveolar macrophages.133 A study explored the influence of functionalization of C60 with molecules presenting different surface charges like hydroxyl groups and amino acids.134 The study concluded that negative charges upregulated TNF-α up-secretion in RAW 264.7 macrophages, but highly positively or negatively charged surfaces increased cell toxicity. |
| T503 | 449-551 | Sentence | denotes | The upregulation of the cytokine TNF-α is a proof that fullerene can promote cellular immune response. |