Id |
Subject |
Object |
Predicate |
Lexical cue |
T229 |
0-219 |
Sentence |
denotes |
To our knowledge, this is the first study showing that mAbs targeting the S2 domain of SARS-CoV-1 can cross-react with SARS-CoV-2 and this observation is consistent with the high sequence conservation in the S2 subunit. |
T230 |
220-426 |
Sentence |
denotes |
The ability of these antibodies, particularly 1A9, to detect SARS-CoV-2 S protein in indirect and sandwich ELISAs demonstrate their utility for detection of SARS-CoV-2 infections in a public health setting. |
T231 |
427-647 |
Sentence |
denotes |
Whether or not the current sensitivity of these antibodies are sufficient for robust detection of SARS-CoV-2 infections in a clinical setting and how they compare to existing PCR-based detection remains to be determined. |
T232 |
648-795 |
Sentence |
denotes |
Successful development of these antibodies into a point of care diagnostic kit will provide a complementary approach to existing detection methods. |
T233 |
796-931 |
Sentence |
denotes |
Besides the mAbs characterised here, several other mAbs have been reported to bind to epitopes in the S2 subunit of SARS-CoV-1 [31-33]. |
T234 |
932-1023 |
Sentence |
denotes |
Thus, it will be important to determine if these mAbs can also cross-react with SARS-CoV-2. |