PMC:7376845 / 29375-30398 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T229 0-219 Sentence denotes To our knowledge, this is the first study showing that mAbs targeting the S2 domain of SARS-CoV-1 can cross-react with SARS-CoV-2 and this observation is consistent with the high sequence conservation in the S2 subunit.
T230 220-426 Sentence denotes The ability of these antibodies, particularly 1A9, to detect SARS-CoV-2 S protein in indirect and sandwich ELISAs demonstrate their utility for detection of SARS-CoV-2 infections in a public health setting.
T231 427-647 Sentence denotes Whether or not the current sensitivity of these antibodies are sufficient for robust detection of SARS-CoV-2 infections in a clinical setting and how they compare to existing PCR-based detection remains to be determined.
T232 648-795 Sentence denotes Successful development of these antibodies into a point of care diagnostic kit will provide a complementary approach to existing detection methods.
T233 796-931 Sentence denotes Besides the mAbs characterised here, several other mAbs have been reported to bind to epitopes in the S2 subunit of SARS-CoV-1 [31-33].
T234 932-1023 Sentence denotes Thus, it will be important to determine if these mAbs can also cross-react with SARS-CoV-2.