| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T162 |
0-110 |
Sentence |
denotes |
Neutrophil activation and neutrophil extracellular traps (NETs) cause endothelial cell glycocalyx injury [49]. |
| T163 |
111-270 |
Sentence |
denotes |
The concentration of circulating histones is directly proportional to the degree of inflammation and end organ dysfunction in trauma or sepsis-like conditions. |
| T164 |
271-379 |
Sentence |
denotes |
Exposure of endothelial cells to histones causes decreased vasodilation and cell death in 25% of cells [50]. |
| T165 |
380-551 |
Sentence |
denotes |
Citrullinated histones 3 (H3CiT) can directly contribute to NET-associated inflammatory responses and opens cell–cell adherans junctions impairing vascular integrity [51]. |
| T166 |
552-782 |
Sentence |
denotes |
The bioactive proteins released from NETs that cause tissue injury include myeloperoxidase (MPO), neutrophil elastase (NE), matrix metalloproteinase (MMP)-9, high-mobility group box (HMGB)-1, proteinase (PTN)-3 and properdin [52]. |
