LitCovid-sentences  

PMC:7366549 / 22386-26331 JSONTXT 11 Projects

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Id Subject Object Predicate Lexical cue
T195 0-10 Sentence denotes Discussion
T196 11-193 Sentence denotes As per the available information, the BtCoV causing human infection belongs to α- and β-CoV genera of the Coronaviridae family. β-CoV genus has five strains known to infect humans25.
T197 194-353 Sentence denotes The two human-infecting strains (NL63 and 229E) from α-CoV genus which cause mild-to-moderate respiratory infections are believed to have originated in bats25.
T198 354-487 Sentence denotes Two members of the β-CoV genus (HCoV-OC43 and HCoV-HKU1) are known to cause the common cold and lower respiratory tract infections26.
T199 488-583 Sentence denotes The other three are now shown to be pathogenic to humans (SARS-CoV-1, MERS-CoV and SARS-CoV-2).
T200 584-673 Sentence denotes The SARS-CoV-1 and SARS-CoV-2 belong to L_B and MERS CoV belongs to L_C of β-CoV genus27.
T201 674-786 Sentence denotes The phylogenetic analysis for the partial RdRp region revealed the presence of distinct BtCoVs in both the bats.
T202 787-869 Sentence denotes The genomic sequences retrieved from the Indian sequences form a distinct cluster.
T203 870-1060 Sentence denotes The three CoV_BtRtBetaCoV/GX2018 sequences retrieved from the Indian Rousettus bats were 5.8-6.7 per cent different from the reference sequence, which was retrieved from Rhinolophus affinis.
T204 1061-1176 Sentence denotes The two CoV_BtRtBetaCoV/GX2018 sequences retrieved from different bats were 1.2 per cent different from each other.
T205 1177-1304 Sentence denotes The effect of host influence on the nt usage of the virus cannot be denied; however, it needs to be explored further in detail.
T206 1305-1422 Sentence denotes Bats are reservoirs for viruses with human pathogenic potential2829, and are known to harbour a broad range of CoVs1.
T207 1423-1611 Sentence denotes The global distribution of bats, along with the different types of cell receptors present within them, favours virus replication, and is a possible link to their intraspecies transmission.
T208 1612-1784 Sentence denotes The interspecies spill-over of a BtCoV to humans is thought to occur through an intermediate host, in which the virus replicates through yet completely unidentified routes.
T209 1785-1906 Sentence denotes In India, regions of the Western Ghats, particularly in Kerala, are reported to have habitat for diverse bat populations.
T210 1907-2039 Sentence denotes The reports of pathogenic human viruses from bat specimens demand enhanced methods to monitor human exposure to various bat species.
T211 2040-2179 Sentence denotes Investigations in unexplored regions/States should be focused on gaining further insights into CoV diversity within Indian bat populations.
T212 2180-2292 Sentence denotes Earlier, we had reported the presence of pathogenic viruses such as the Nipah virus in Pteropus bats in India16.
T213 2293-2459 Sentence denotes In the present scenario of changing demography and ecological manipulations, it is challenging to have checks on the encounters of bats with other animals and humans.
T214 2460-2646 Sentence denotes Therefore, active and continuous surveillance remains crucial for outbreak alerts for bat-associated viral agents with epidemic potential, which would be helpful in timely interventions.
T215 2647-2921 Sentence denotes Although CoVs in the subfamily Coronavirinae do not usually produce clinical symptoms in their natural hosts (bats), accidental transmission of these viruses to humans and other animals may result in respiratory, enteric, hepatic or neurologic diseases of variable severity.
T216 2922-2995 Sentence denotes It is still not understood as to why only certain CoVs can infect people.
T217 2996-3069 Sentence denotes There is a need of proactive surveillance of zoonotic infections in bats.
T218 3070-3286 Sentence denotes Detection and identifications of such aetiological agents will provide leads for the development of diagnostic along with preparedness and readiness to deal with such emergent viruses thereby quickly containing them.
T219 3287-3475 Sentence denotes The detection and identification of such viruses from bats also recommends cross-sectional antibody surveys (human and domestic animals) in localities where the viruses have been detected.
T220 3476-3578 Sentence denotes Similarly, if epidemiological situation demands, evidence-based surveillance should also be conducted.
T221 3579-3746 Sentence denotes There is a need of developing strong mechanisms for working jointly with various stakeholders such as wildlife, poultry, animal husbandry and human health departments.
T222 3747-3838 Sentence denotes In conclusion, our study showed detection of pathogenic CoVs in two species of Indian bats.
T223 3839-3945 Sentence denotes Continuous active surveillance is required to identify the emerging novel viruses with epidemic potential.