Id |
Subject |
Object |
Predicate |
Lexical cue |
T232 |
0-36 |
Sentence |
denotes |
6 Conclusions & future perspectives |
T233 |
37-200 |
Sentence |
denotes |
Polysaccharides have a long history to be used as important active ingredients in traditional Chinese medicine due to their extensive activity and reliable safety. |
T234 |
201-293 |
Sentence |
denotes |
Polysaccharides have broad spectrum of antiviral activities and unique antiviral mechanisms. |
T235 |
294-522 |
Sentence |
denotes |
They can exert antiviral effects by interfering with the life cycle of virus, or can indirectly exert antiviral activities by enhancing the body's immunity, which makes them have a great application prospect in anti-coronavirus. |
T236 |
523-760 |
Sentence |
denotes |
GAGs, marine polysaccharides such as carrageenan and chitosan, traditional Chinese medicine polysaccharides such as APS and LNT, and their derivatives, have shown potent anti-coronavirus activity and multiple anti-coronavirus mechanisms. |
T237 |
761-878 |
Sentence |
denotes |
We speculate that polysaccharides will exert anti-SARS-CoV-2 effects by the possible mechanisms as shown in Fig. 10 . |
T238 |
879-1030 |
Sentence |
denotes |
More importantly, polysaccharide-based vaccine adjuvants, nanomaterials, and drug delivery systems will play important roles in anti-coronavirus field. |
T239 |
1031-1276 |
Sentence |
denotes |
Based on the immunomodulation and antiviral activity of polysaccharides, combined with nanotechnology, we put forward the strategy of loading S or N protein of coronavirus onto polysaccharide capped AuNPs vaccine for COVID-19 treatment (Fig. 9). |
T240 |
1277-1370 |
Sentence |
denotes |
This review may provide a novel idea for the development of anti-COVID-19 drugs and vaccines. |
T241 |
1371-1438 |
Sentence |
denotes |
Fig. 10 The proposed mechanisms of polysaccharides anti-SARS-CoV-2. |