PMC:7358770 / 37634-39072 JSONTXT 9 Projects

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Id Subject Object Predicate Lexical cue
T232 0-36 Sentence denotes 6 Conclusions & future perspectives
T233 37-200 Sentence denotes Polysaccharides have a long history to be used as important active ingredients in traditional Chinese medicine due to their extensive activity and reliable safety.
T234 201-293 Sentence denotes Polysaccharides have broad spectrum of antiviral activities and unique antiviral mechanisms.
T235 294-522 Sentence denotes They can exert antiviral effects by interfering with the life cycle of virus, or can indirectly exert antiviral activities by enhancing the body's immunity, which makes them have a great application prospect in anti-coronavirus.
T236 523-760 Sentence denotes GAGs, marine polysaccharides such as carrageenan and chitosan, traditional Chinese medicine polysaccharides such as APS and LNT, and their derivatives, have shown potent anti-coronavirus activity and multiple anti-coronavirus mechanisms.
T237 761-878 Sentence denotes We speculate that polysaccharides will exert anti-SARS-CoV-2 effects by the possible mechanisms as shown in Fig. 10 .
T238 879-1030 Sentence denotes More importantly, polysaccharide-based vaccine adjuvants, nanomaterials, and drug delivery systems will play important roles in anti-coronavirus field.
T239 1031-1276 Sentence denotes Based on the immunomodulation and antiviral activity of polysaccharides, combined with nanotechnology, we put forward the strategy of loading S or N protein of coronavirus onto polysaccharide capped AuNPs vaccine for COVID-19 treatment (Fig. 9).
T240 1277-1370 Sentence denotes This review may provide a novel idea for the development of anti-COVID-19 drugs and vaccines.
T241 1371-1438 Sentence denotes Fig. 10 The proposed mechanisms of polysaccharides anti-SARS-CoV-2.