Id |
Subject |
Object |
Predicate |
Lexical cue |
T191 |
0-239 |
Sentence |
denotes |
Although SARS-CoV vaccines can protect against lethal infection, the addition of delta inulin-based polysaccharide adjuvant on day 3 post-challenge can significantly increase serum neutralizing-antibody titers and reduce lung virus titers. |
T192 |
240-400 |
Sentence |
denotes |
It also shows that immunity achieved with delta inulin adjuvants is long-lived, thereby overcoming the natural tendency for rapidly waning coronavirus immunity. |
T193 |
401-529 |
Sentence |
denotes |
This suggests that delta inulin polysaccharide adjuvants have the potential to develop more effective coronavirus vaccines [20]. |
T194 |
530-653 |
Sentence |
denotes |
In addition, some Chinese herbal medicinal polysaccharides have been used as safe and effective adjuvants [77,107,112,113]. |
T195 |
654-800 |
Sentence |
denotes |
APS as an adjuvant combined with influenza vaccine can improve the immune response and systemic humoral response to H5N1 virus infection [46,114]. |
T196 |
801-974 |
Sentence |
denotes |
APS can potentially be used as an immunomodulator for a foot-and-mouth disease virus (FMDV), which is an RNA virus vaccine, and provide better protection against FMDV [115]. |
T197 |
975-1182 |
Sentence |
denotes |
APS is also a potent adjuvant for hepatitis B DNA vaccine, and can enhance the immune responses of HBV DNA vaccine via promoting dendritic cells maturation and inhibit the regulatory T cells frequency [116]. |
T198 |
1183-1341 |
Sentence |
denotes |
Polysaccharide extract from RI exerts potent anti-IAV activity against human seasonal influenza viruses (H1N1 and H3N2) and AIV (H6N2 and H9N2) in vitro [49]. |
T199 |
1342-1511 |
Sentence |
denotes |
The polysaccharides also significantly reduced the expression of pro-inflammatory cytokines (IL-6) and strongly inhibited the protein expression of TLR-3 induced by PR8. |
T200 |
1512-1663 |
Sentence |
denotes |
The polysaccharide extract from RI, therefore, has the potential to be used as an adjunct to antiviral therapy for the treatment of IAV infection [49]. |