| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T155 |
0-51 |
Sentence |
denotes |
3.3 Inhibiting viral transcription and replication |
| T156 |
52-203 |
Sentence |
denotes |
Polysaccharides, especially sulfated polysaccharides, can directly interfere with viral replication related enzymes and relevant targets in host cells. |
| T157 |
204-405 |
Sentence |
denotes |
Iota-carrageenan can effectively inhibit porcine reproductive and respiratory syndrome virus (PRRSV) replication at mRNA and protein levels in both Marc-145 cells and porcine alveolar macrophages [98]. |
| T158 |
406-599 |
Sentence |
denotes |
Carrageenan oligosaccharide and its sulphated derivative have good inhibitory effects on IAV replication both in vitro and in vivo, while not seem to be dependent on the interferon system [99]. |
| T159 |
600-768 |
Sentence |
denotes |
Sulfated polysaccharide from Gracilaria lemaneiformis shows anti-influenza virus activities in vitro by inhibiting viral adsorption and replication on host cells [100]. |
| T160 |
769-995 |
Sentence |
denotes |
Polysaccharides isolated from Grifola frondosa showed resistance against enterovirus 71, a positive-stranded RNA virus, by blocking viral replication and inhibiting viral VP1 protein expression and genomic RNA synthesis [101]. |
| T161 |
996-1222 |
Sentence |
denotes |
The virus replication was inhibited by a sulfated polysaccharide from Angelica sinensis, which is a commonly used traditional Chinese herbal medicine, at the dose of 10 and 30 mg/kg (26% and 30% inhibition respectively) [102]. |
| T162 |
1223-1375 |
Sentence |
denotes |
APS has a long-lasting inhibitory effect on HBV replication in vivo, which can be used as a supplementary modality to treat hepatitis B infection [103]. |
| T163 |
1376-1475 |
Sentence |
denotes |
Furthermore, APS can inhibit the replication of avian IBV in vitro in a dose-dependent manner [78]. |
