| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T282 |
0-151 |
Sentence |
denotes |
miR-129-2-3p, here identified as a common mutated miR, has previously been identified as a regulator in human cancer development and progression [106]. |
| T283 |
152-295 |
Sentence |
denotes |
It has been identified as a diagnostic and prognostic biomarker for renal cell carcinoma [107] and a suppressor of serous ovarian cancer [104]. |
| T284 |
296-499 |
Sentence |
denotes |
Its upregulation suppresses breast cancer cell proliferation and induces its apoptosis, while downregulation, via hypermethylation, increases breast cancer progression due to BCL2L2 overexpression [107]. |
| T285 |
500-746 |
Sentence |
denotes |
It furthermore attenuates cell migration and invasion in renal cell carcinoma by affecting the downregulation of various metastasis-related genes [108]. miR129-2 has been linked to a range of haematological malignancies, including lymphoma [109]. |
| T286 |
747-883 |
Sentence |
denotes |
It is also linked to lung adenocarcinoma including regulation of cell proliferation [110], as well as to hepatocellular carcinoma [111]. |
| T287 |
884-1077 |
Sentence |
denotes |
Interestingly, miR-129-2-3p has been found to be upregulated in human papilloma virus-positive (HPV) head and neck squamous cell carcinoma [112] and in HPV transfected keratinocyte cells [113]. |
| T288 |
1078-1249 |
Sentence |
denotes |
In the light of increasing understanding of the link between SARS-CoV-2 and comorbidities, underlying changes in miR-129-2-3p expression may be of considerable importance. |
