Id |
Subject |
Object |
Predicate |
Lexical cue |
T236 |
0-74 |
Sentence |
denotes |
In addition, it was shown that miR-3934-3p downregulated TGFBR1 and SMAD3. |
T237 |
75-175 |
Sentence |
denotes |
In a similar vein, HSV-1 viral infection led to a significant down-regulation of these targets [74]. |
T238 |
176-311 |
Sentence |
denotes |
Moreover, the activation of the TGF-β/Smad pathway is critical for lung fibrosis, which was previously shown in SARS-CoV-related cases. |
T239 |
312-434 |
Sentence |
denotes |
Dysregulation of ACE2 may influence the toll-receptor signalling pathway, via IL6, and affect downstream immune responses. |
T240 |
435-596 |
Sentence |
denotes |
Irrespective of SARS-CoV-2 or pneumonia in TCGA-LUAD, the altered immunoreaction was the primary cause (lung adenocarcinoma; SARS-CoV-2; ACE2; miR-125b-5p; IL6). |
T241 |
597-803 |
Sentence |
denotes |
TGF-β and cigarette smoke have been shown to suppress miR-141-5p to promote CCR5 expression on primary bronchial epithelial cells, which results in increased viral entry and infection by R5-tropic HIV [75]. |
T242 |
804-1073 |
Sentence |
denotes |
Given that TGF-β signalling is upregulated by trans-activator (Tat) protein, cigarette smoke and in chronic lung diseases, it has been determined the effects of persistent TGF-β signalling on HIV infection in primary bronchial epithelium re-differentiated ex vivo [75]. |
T243 |
1074-1284 |
Sentence |
denotes |
In our current study, miR-3934-3p was found to be associated with KEGG pathways for glycosaminoglycan biosynthesis heparan sulfate/heparin, mucin type O-glycan biosynthesis and vitamin digestion and absorption. |
T244 |
1285-1331 |
Sentence |
denotes |
The relevance of these pathways is as follows: |