| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T770 |
0-141 |
Sentence |
denotes |
As CLQ interacts with the GM1 sugar part, the N-terminal domain of the S protein loses viral attachment capacity to the cell receptors [166]. |
| T771 |
142-374 |
Sentence |
denotes |
The S protein NTD and the CLQ/CLQ-OH maintain the same position during GM1 binding, consequently preventing GM1 binding to the S protein and the drug at the same time, because the NTD and the CLQ/CLQ-OH simultaneously recognize GM1. |
| T772 |
375-491 |
Sentence |
denotes |
Asn-167 forms a hydrogen bond with the GalNAc residue, whereas an aromatic Phe-135 stacks to the Glc residue of GM1. |
| T773 |
492-651 |
Sentence |
denotes |
Therefore, the antiviral activities of CLQ and CLQ-OH is to block the interaction between the SARS-CoV-2 S glycoprotein and gangliosides on host cell surfaces. |
| T774 |
652-779 |
Sentence |
denotes |
The lipid composition of host cell PM can also be a potential target for preventive and therapeutic drugs against such viruses. |
