| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T57 |
0-92 |
Sentence |
denotes |
The 9-carbon SAs are mainly animal-specific with anionic sugars attached to terminal sugars. |
| T58 |
93-133 |
Sentence |
denotes |
SAs exist in two forms, NeuGc and NeuAc. |
| T59 |
134-206 |
Sentence |
denotes |
NeuGc is a differentially modified form of the parental SA form, Neu5Ac. |
| T60 |
207-236 |
Sentence |
denotes |
SAs are structurally diverse. |
| T61 |
237-580 |
Sentence |
denotes |
For example, several modified SA forms are known for their structures including neuraminic acid (NeuC), N-acetyl neuraminic acid (NeuAc), N-glycolyl neuraminic acid (NeuGc), N,O-diacetyl neuraminic acid (occurs in horses), N,O-diacetyl neuraminic acid (occurs in bovines) and N-acetyl O-diacetyl neuraminic acid (occurs in bovines) (Figure 2). |
| T62 |
581-642 |
Sentence |
denotes |
Sialyltransferases (STs) biosynthesize different SA linkages. |
| T63 |
643-740 |
Sentence |
denotes |
SA linkage diversity occurs at the α2-3, α2-6, α2-8 or α2-9 to the SA or Gal residues (Figure 3). |
| T64 |
741-875 |
Sentence |
denotes |
For example, in formation of α2,3 SA or α2,6 SA structures, α2,3-ST and α2,6-ST utilize substrates such as Galβ-1,4-GlcNAc (Figure 4). |
| T65 |
876-982 |
Sentence |
denotes |
The most frequent modification of SAs is O-acetylation at positions of C4, C7, C8 and C9 of SA (Figure 5). |
