LitCovid-sentences  

PMC:7352545 / 71521-72675 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T692 0-73 Sentence denotes Plasma sera prepared from infected patients is an alternative medication.
T693 74-164 Sentence denotes The WHO has suggested this trial since the 2014 Ebola epidemic and 2015 MERS-CoV outbreak.
T694 165-208 Sentence denotes In addition, Mab therapy is another option.
T695 209-336 Sentence denotes For example, LCA50 Mab mimics produced by modification of plasma antibodies isolated from MERS-CoV patients was valuable [140].
T696 337-456 Sentence denotes Low molecular molecules are being examined for anti-virus activities from alkaloids, glycan derivatives and terpenoids.
T697 457-560 Sentence denotes Recently, anti-CoV drugs are being approached using molecular modeling, docking and simulation methods.
T698 561-692 Sentence denotes Computation-assisted drugs via molecular modeling and docking toward drug targets are applied as anti-viral compounds against CoVs.
T699 693-728 Sentence denotes They target human ACE2, PLpro (PDB:
T700 729-765 Sentence denotes 3e9s), the CoV main proteinase (PDB:
T701 766-933 Sentence denotes 6Y84), 3-chymotrypsin-like (3C-like protease; 3CLpro), RdRp, helicase, N7 methyltransferase, human DDP4, RBD, protease cathepsin L, type II TM Ser protease or TMPRSS2.
T702 934-950 Sentence denotes CoV 3CLpro (PDB:
T703 951-1022 Sentence denotes 6WX4) and the PLpro cleave the polyproteins to assemble virus proteins.
T704 1023-1154 Sentence denotes For newborn RNA genomes, RdRp is used as a replicase for the complementary RNA strand synthesis, which uses the virus RNA template.