Id |
Subject |
Object |
Predicate |
Lexical cue |
T625 |
0-6 |
Sentence |
denotes |
6.3.9. |
T626 |
7-103 |
Sentence |
denotes |
Tetraspanin CD9 is a Surface factor for MERS-CoV Entry Via Scaffold Cell Receptors and Proteases |
T627 |
104-290 |
Sentence |
denotes |
Tetraspanin CD9, but not tetraspanin CD81, associates with DPP4 and the type II TM serine protease (TTSP) member TMPRSS2, a CoV-activating protease, to form a cell surface complex [131]. |
T628 |
291-379 |
Sentence |
denotes |
This CD9–DPP4–TMPRSS2 complex permits MERS-CoV pseudovirus entrance into the host cells. |
T629 |
380-494 |
Sentence |
denotes |
The tetraspanins have four TM spanning regions linked by one large and one small loop in the extracellular region. |
T630 |
495-561 |
Sentence |
denotes |
Tetraspanins form virus entry baselines and open CoV entry routes. |
T631 |
562-652 |
Sentence |
denotes |
To help viral entry into host cells, MERS-CoV S interacts with DPP4 receptors via the RBD. |
T632 |
653-747 |
Sentence |
denotes |
Receptor involvement causes cleavage using proteases such as the previously described TMPRSS2. |
T633 |
748-837 |
Sentence |
denotes |
Association of tetraspanin CD9 with the DPP4–TMPRSS2 complex triggers the S glycoprotein. |
T634 |
838-923 |
Sentence |
denotes |
MERS-CoVs enter the cells via endocytosis and cathepsins cleave the S proteins [132]. |