| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T549 |
0-84 |
Sentence |
denotes |
Both raft and non-raft CEACAMs are involved in the virus–cell membrane fusion event. |
| T550 |
85-245 |
Sentence |
denotes |
Formation of CEACAM-associated MHV particles or CEACAM-induced MHV fusion is possible by GPI-anchored CEACAMs through the binding between CEACAM and S proteins. |
| T551 |
246-383 |
Sentence |
denotes |
However, MHV can bind to both GPI- and TM-anchored CEACAMs. In addition, soluble CEACAMs also mediate S glycoprotein-driven fusion [104]. |
| T552 |
384-451 |
Sentence |
denotes |
This implies that membrane anchors are not intrinsically necessary. |
| T553 |
452-525 |
Sentence |
denotes |
In fact, CEACAMs are present in different tissue-specific isoforms [105]. |
| T554 |
526-777 |
Sentence |
denotes |
Nevertheless, GPI-anchored CEACAMs are more effective for MHV infection than TM-anchored CEACAMs. Soluble CEACAM receptors can bind to viral S glycoproteins and induce conformational shifts to acceptable S glycoprotein-involved membrane fusions [106]. |
| T555 |
778-931 |
Sentence |
denotes |
For example, soluble CEACAM forms interacts with S1 fragments [107] and alters the S1–S2 association stability [108] and S1 oxidation confirmation [109]. |
| T556 |
932-993 |
Sentence |
denotes |
S proteins are structurally shifted prior to membrane fusion. |
| T557 |
994-1150 |
Sentence |
denotes |
For the cross-linking of viruses and cells, integral hydrophobic peptides of the S2 chain are embedded into membranes via membrane hydrophobic cholesterols. |
