Id |
Subject |
Object |
Predicate |
Lexical cue |
T520 |
0-43 |
Sentence |
denotes |
The Ser exopeptidase DPP-4/human CD26 (PDB: |
T521 |
44-126 |
Sentence |
denotes |
4L72), a type II TM ectopeptidase, functions as a host cell receptor for MERS-CoV. |
T522 |
127-237 |
Sentence |
denotes |
The RBD structure was characterized by crystallography approaches of the MERS-CoV S glycoprotein–DPP4 complex. |
T523 |
238-371 |
Sentence |
denotes |
DPP4 is a single type II TM glycoprotein with a small cytoplasmic tail in the N-terminal region and is present as a homodimeric form. |
T524 |
372-433 |
Sentence |
denotes |
DPP4 cleaves X-proline dipeptides from the N-terminal region. |
T525 |
434-533 |
Sentence |
denotes |
S glycoprotein recognizes SA species and DPP44 as the attachment and entry receptors, respectively. |
T526 |
534-611 |
Sentence |
denotes |
The MERS-CoV S1 N-terminal domain attaches to DPP4 as the host receptor [81]. |
T527 |
612-681 |
Sentence |
denotes |
The S2 C-terminal domain of MERS-CoV anchors to cellular PM to enter. |
T528 |
682-766 |
Sentence |
denotes |
MERS-CoV S glycoprotein is cleaved at a sequence between the S1 and S2 domains [96]. |
T529 |
767-821 |
Sentence |
denotes |
Another cleavage site S2′ is present in the S2 domain. |
T530 |
822-990 |
Sentence |
denotes |
MERS CoV S glycoprotein sialyl receptors are expressed in the camel nasal respiratory epithelial cells and the human lung alveolar epithelial cells, which express DPP4. |
T531 |
991-1080 |
Sentence |
denotes |
Binding capacities are hindered by the SA 9-O-acetyl group or SA 5-N-glycolyl group [75]. |