PMC:7352545 / 53978-55058 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T520 0-43 Sentence denotes The Ser exopeptidase DPP-4/human CD26 (PDB:
T521 44-126 Sentence denotes 4L72), a type II TM ectopeptidase, functions as a host cell receptor for MERS-CoV.
T522 127-237 Sentence denotes The RBD structure was characterized by crystallography approaches of the MERS-CoV S glycoprotein–DPP4 complex.
T523 238-371 Sentence denotes DPP4 is a single type II TM glycoprotein with a small cytoplasmic tail in the N-terminal region and is present as a homodimeric form.
T524 372-433 Sentence denotes DPP4 cleaves X-proline dipeptides from the N-terminal region.
T525 434-533 Sentence denotes S glycoprotein recognizes SA species and DPP44 as the attachment and entry receptors, respectively.
T526 534-611 Sentence denotes The MERS-CoV S1 N-terminal domain attaches to DPP4 as the host receptor [81].
T527 612-681 Sentence denotes The S2 C-terminal domain of MERS-CoV anchors to cellular PM to enter.
T528 682-766 Sentence denotes MERS-CoV S glycoprotein is cleaved at a sequence between the S1 and S2 domains [96].
T529 767-821 Sentence denotes Another cleavage site S2′ is present in the S2 domain.
T530 822-990 Sentence denotes MERS CoV S glycoprotein sialyl receptors are expressed in the camel nasal respiratory epithelial cells and the human lung alveolar epithelial cells, which express DPP4.
T531 991-1080 Sentence denotes Binding capacities are hindered by the SA 9-O-acetyl group or SA 5-N-glycolyl group [75].