PMC:7352545 / 36742-37829 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T359 0-104 Sentence denotes In γ-CoVs, IBV strains, known as poultry respiratory infectious pathogens, can agglutinate erythrocytes.
T360 105-206 Sentence denotes IBV prefers to recognize α2,3-NeuAc and the SA functions as a host entry receptor for infection [66].
T361 207-385 Sentence denotes Glycosylation of IBV M41 S1 protein RBD is crucial for interaction with chicken trachea tissue and RBD N-glycosylation confers receptor specificity and enables virus replication.
T362 386-444 Sentence denotes The heavy glycosylated M41 RBD has 10 glycosylation sites.
T363 445-500 Sentence denotes N-glycosylation of IBV determines receptor specificity.
T364 501-551 Sentence denotes However, the host receptor has not yet been found.
T365 552-638 Sentence denotes NA treatment reduces the binding of soluble S to kidney and tracheal epithelial cells.
T366 639-710 Sentence denotes The IBV S protein recognizes epithelial cells in a SA-dependent manner.
T367 711-840 Sentence denotes The SA-binding ability of IBV is necessary for infection of tracheal epithelial cells and lung respiratory epithelial cells [67].
T368 841-956 Sentence denotes The SA-binding site is located on S1 of the IBV S protein, although the IBV-specific protein receptor is not known.
T369 957-1008 Sentence denotes In contrast to BCoV or HCoV-OC43, IBV lacks an RDE.
T370 1009-1087 Sentence denotes SA binding of IBV is likely more essential than in other viruses such as TGEV.