PMC:7352545 / 36721-37829 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T358 0-20 Sentence denotes 6.1.3. γ-Coronavirus
T359 21-125 Sentence denotes In γ-CoVs, IBV strains, known as poultry respiratory infectious pathogens, can agglutinate erythrocytes.
T360 126-227 Sentence denotes IBV prefers to recognize α2,3-NeuAc and the SA functions as a host entry receptor for infection [66].
T361 228-406 Sentence denotes Glycosylation of IBV M41 S1 protein RBD is crucial for interaction with chicken trachea tissue and RBD N-glycosylation confers receptor specificity and enables virus replication.
T362 407-465 Sentence denotes The heavy glycosylated M41 RBD has 10 glycosylation sites.
T363 466-521 Sentence denotes N-glycosylation of IBV determines receptor specificity.
T364 522-572 Sentence denotes However, the host receptor has not yet been found.
T365 573-659 Sentence denotes NA treatment reduces the binding of soluble S to kidney and tracheal epithelial cells.
T366 660-731 Sentence denotes The IBV S protein recognizes epithelial cells in a SA-dependent manner.
T367 732-861 Sentence denotes The SA-binding ability of IBV is necessary for infection of tracheal epithelial cells and lung respiratory epithelial cells [67].
T368 862-977 Sentence denotes The SA-binding site is located on S1 of the IBV S protein, although the IBV-specific protein receptor is not known.
T369 978-1029 Sentence denotes In contrast to BCoV or HCoV-OC43, IBV lacks an RDE.
T370 1030-1108 Sentence denotes SA binding of IBV is likely more essential than in other viruses such as TGEV.