| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T187 |
0-189 |
Sentence |
denotes |
SAs have various derivatives of more than 50 chemically different structures formed from the basic N-acetylneuraminic acid (Neu5Ac) on the main ring of pyranose and the glycerol side chain. |
| T188 |
190-298 |
Sentence |
denotes |
SA are modified by acetyl-, lactyl-, methyl- and sulfo-groups individually or in multiple combinations [28]. |
| T189 |
299-355 |
Sentence |
denotes |
Multiple enzymes are involved in the modifications [29]. |
| T190 |
356-494 |
Sentence |
denotes |
Historically, the first discovered SA was crystallized by Gunner Blix via a hot mild acid extraction of bovine submaxillary mucin in 1936. |
| T191 |
495-529 |
Sentence |
denotes |
It consisted of two acetyl groups. |
| T192 |
530-595 |
Sentence |
denotes |
Among these, only one acetyl group was attached to nitrogen [30]. |
| T193 |
596-748 |
Sentence |
denotes |
Blix isolated a 9-O-acetyl SA of the common SA N-acetylneuraminic acid (Neu5Ac), chemically described as 9-O-acetyl-N-acetylneuraminic acid (Neu5,9Ac2). |
| T194 |
749-824 |
Sentence |
denotes |
Neu5,9Ac2, Neu5Ac and Neu5Gc are naturally occurring SA species in mammals. |
| T195 |
825-864 |
Sentence |
denotes |
A common modification is O-acetylation. |
| T196 |
865-918 |
Sentence |
denotes |
In fact, O-acetylation of SAs is common in organisms. |
