Id |
Subject |
Object |
Predicate |
Lexical cue |
T140 |
0-4 |
Sentence |
denotes |
3.2. |
T141 |
5-29 |
Sentence |
denotes |
Nucleocapsid (N) Protein |
T142 |
30-92 |
Sentence |
denotes |
In RNA viruses, the N protein recognizes the viral RNA genome. |
T143 |
93-112 |
Sentence |
denotes |
The N protein (PDB: |
T144 |
113-163 |
Sentence |
denotes |
6M3M) binds to the RNA genome via the NTD and CTD. |
T145 |
164-245 |
Sentence |
denotes |
The N protein tethers to the viral RNA and replicase–transcriptase complex (RTC). |
T146 |
246-256 |
Sentence |
denotes |
NSP3 (PDB: |
T147 |
257-314 |
Sentence |
denotes |
6VXS) of CoV blocks the innate immune responses of hosts. |
T148 |
315-497 |
Sentence |
denotes |
After entrance into the host cells, for CoV transcription and particle release, RNA chaperones such as nonspecific nucleic acid binding proteins potentiate ssRNA conformation shifts. |
T149 |
498-568 |
Sentence |
denotes |
Representatively, the N protein is known as the RNA chaperone protein. |
T150 |
569-741 |
Sentence |
denotes |
For example, glycogen synthase kinase 3 (GSK3) phosphorylates the SARS-CoV N-protein and thus, GSK3 inhibition contributes to reduced replication activity of SARS-CoV [19]. |
T151 |
742-1018 |
Sentence |
denotes |
In addition, heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) regulates the preformed mRNA splicing in the nucleus and continuous translation. hnRNPA1 interacts with SARS-CoV N protein to form a replication and transcription complex during ssRNA genome biosynthesis [20]. |