PMC:7346000 / 25760-27751 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T136 0-83 Sentence denotes Bacterial, fungal and viral secondary infections or co-infections affect mortality.
T137 84-225 Sentence denotes Acinetobacter baumanii, Klebsiella pneumonia and Aspergillus species are important nosocomial pathogens [93] complicating the disease course.
T138 226-333 Sentence denotes Studies from France [51], Germany [50], Belgium [52], and the Netherlands [47], underline the role of CAPA.
T139 334-432 Sentence denotes Diagnosing co-infections is complex and rapid diagnosis plays a crucial role in this setting [49].
T140 433-601 Sentence denotes Close monitoring for infection development is needed, as well as longitudinal sampling throughout the disease course using culture dependent and independent techniques.
T141 602-772 Sentence denotes Aspergillus antigen and PCR testing of respiratory fluids should be a routine procedure for critically ill patients [94], specifically for those suffering from ARDS [50].
T142 773-883 Sentence denotes Co-infection with human metapneumovirus has been reported in two of five cases in the German CAPA series [50].
T143 884-1072 Sentence denotes It is unknown whether hospitals caring for COVID-19 test comprehensive respiratory pathogen panels, and to date no analysis of mixed viral infection in COVID-19 patients has been reported.
T144 1073-1210 Sentence denotes In the context of COVID-19, mixed viral infection may be misinterpreted as presence of innocent bystanders and thus remain underreported.
T145 1211-1324 Sentence denotes With bronchoalveolar lavage and autopsy regarded as high-risk procedures, key diagnostic instruments are lacking.
T146 1325-1483 Sentence denotes Autopsy studies are key to understanding pathophysiology of COVID-19 [95] and are critically enlighten interaction between SARS-CoV-2 and different pathogens.
T147 1484-1640 Sentence denotes With availability of lower respiratory samples, normally obtained by BALF, the quality of microbiological and virological work up would be greatly improved.
T148 1641-1769 Sentence denotes Inspection of trachea and bronchi is achieved by bronchoscopy, which is critical to find possible Aspergillus tracheobronchitis.
T149 1770-1991 Sentence denotes Thus, physicians face the dilemma of taking the hazard of aerosolization of SARS-CoV-2, risking transmission versus the endeavor of facilitating the optimal diagnosis and treatment to the patients entrusted to their care.