| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T87 |
0-80 |
Sentence |
denotes |
IPA is known to be problematic to diagnose in the non-neutropenic ICU host [23]. |
| T88 |
81-357 |
Sentence |
denotes |
Regardless of the compelling evidence for CAPA in this patient, the EORTC/MSGERC [24] host criteria for invasive fungal disease were not met, nor did the patient meet the AspICU algorithm because we tested tracheal aspirates instead of bronchoalveolar lavage (BAL) fluid [25]. |
| T89 |
358-488 |
Sentence |
denotes |
This is in line with findings from other groups, where CAPA patients did not meet the EORTC/MSGERC host criteria either [3,4,5,6]. |
| T90 |
489-721 |
Sentence |
denotes |
In addition, the American Association for Bronchology and Interventional Pulmonology (AABIP) has issued a statement advising against routine bronchoscopy in COVID-19 patients, as it poses substantial risk to patients and staff [26]. |
| T91 |
722-871 |
Sentence |
denotes |
BAL should only be considered in intubated patients if upper respiratory samples are negative and BAL would significantly change clinical management. |
| T92 |
872-1012 |
Sentence |
denotes |
Tracheal aspirate cultures, as performed twice weekly in our patient, repeatedly identified A. fumigatus as the only micro-organism present. |
| T93 |
1013-1160 |
Sentence |
denotes |
In the first positive culture, five colonies were tested for resistance with the VIPcheck plate as is recommended to exclude azole resistance [15]. |
| T94 |
1161-1431 |
Sentence |
denotes |
When surveillance cultures of tracheal aspirates were persistently cultured positive with A. fumigatus during voriconazole therapy, we suspected the selection of resistant isolates which were probably already present in the first samples, albeit in undetectable numbers. |
| T95 |
1432-1471 |
Sentence |
denotes |
An autopsy to confirm IPA was not done. |
