PMC:7340597 / 12575-15049 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T102 0-34 Sentence denotes 3.2 Case 1 – Organizing pneumonia
T103 35-193 Sentence denotes A 77-year old male without significant medical history was evaluated in our emergency department (ED) with complaints of general weakness, fever and dyspnoea.
T104 194-408 Sentence denotes Initial chest CT showed extensive bilateral areas of ground-glass opacity with both central and peripheral distribution, patchy subpleural non-dependant consolidations and areas with subpleural sparing (Fig. 1-1A).
T105 409-568 Sentence denotes Soon after admission patient was in need of mechanical ventilatory support and developed acute renal failure for which renal replacement therapy was initiated.
T106 569-784 Sentence denotes After six days of mechanical ventilation chest CT-angiography showed pulmonary emboli along with new areas of ground-glass opacity and progression of dens subpleural consolidations with air-bronchograms (Fig. 1-1B).
T107 785-843 Sentence denotes A nosocomial infection was ruled out by bronchial culture.
T108 844-1008 Sentence denotes Patient's neurologic status deteriorated and CT head revealed brain ischemia due to infarction of the area supplied by the left and right posterior cerebral artery.
T109 1009-1050 Sentence denotes The patient died 12 days after admission.
T110 1051-1159 Sentence denotes Postmortem pathologic examination revealed that the overall architecture of the lung tissue remained intact.
T111 1160-1292 Sentence denotes However, a prominent amount of fibromyxoid or fibroblastic bodies was present in the alveoli with surrounding histiocytes (Fig. 2A .
T112 1293-1366 Sentence denotes The extent of involved lung tissue was estimated at around 25% (Table 2).
T113 1367-1451 Sentence denotes No remnants of hyaline membranes or prominent alveolar fibrinous exudate were found.
T114 1452-1590 Sentence denotes Microthrombi in small blood vessels of the alveolar septa were seen, as well as an organizing thrombus in a larger sized vessel (Fig. 2E).
T115 1591-1705 Sentence denotes The histologic findings in this case point towards an epithelial, and vascular phenotype of a SARS-CoV2 infection.
T116 1706-1746 Sentence denotes No fungi were present in de PAS-D stain.
T117 1747-1817 Sentence denotes This histologic pattern is characteristic for an organizing pneumonia.
T118 1818-1851 Sentence denotes Fig. 2 Microscopic lung findings.
T119 1852-2474 Sentence denotes A, case 1: intra-alveolar fibroblastic bodies, consistent with organizing pneumonia, (H&E, 10×) B, case 2: loss of alveolar architecture with extensive fibrosis (H&E; 10×) C, case 3: inflammatory infiltrate with neutrophils and lymphocytes, note the hyaline membranes (arrows), suggestive for diffuse alveolar damage. (H&E, 20×) D, case 4: prominent fibrinous exudate in alveoli as seen in AFOP (H&E; 10×) E: thrombus in larger vessel (H&E, 5×) F: cytopathogenic changes in pneumocytes due to viral infection seen in all cases: hyperplasia, multinucleated giant cells (asterisks), intranuclear inclusion bodies (H&E, 40×).