Id |
Subject |
Object |
Predicate |
Lexical cue |
T102 |
0-34 |
Sentence |
denotes |
3.2 Case 1 – Organizing pneumonia |
T103 |
35-193 |
Sentence |
denotes |
A 77-year old male without significant medical history was evaluated in our emergency department (ED) with complaints of general weakness, fever and dyspnoea. |
T104 |
194-408 |
Sentence |
denotes |
Initial chest CT showed extensive bilateral areas of ground-glass opacity with both central and peripheral distribution, patchy subpleural non-dependant consolidations and areas with subpleural sparing (Fig. 1-1A). |
T105 |
409-568 |
Sentence |
denotes |
Soon after admission patient was in need of mechanical ventilatory support and developed acute renal failure for which renal replacement therapy was initiated. |
T106 |
569-784 |
Sentence |
denotes |
After six days of mechanical ventilation chest CT-angiography showed pulmonary emboli along with new areas of ground-glass opacity and progression of dens subpleural consolidations with air-bronchograms (Fig. 1-1B). |
T107 |
785-843 |
Sentence |
denotes |
A nosocomial infection was ruled out by bronchial culture. |
T108 |
844-1008 |
Sentence |
denotes |
Patient's neurologic status deteriorated and CT head revealed brain ischemia due to infarction of the area supplied by the left and right posterior cerebral artery. |
T109 |
1009-1050 |
Sentence |
denotes |
The patient died 12 days after admission. |
T110 |
1051-1159 |
Sentence |
denotes |
Postmortem pathologic examination revealed that the overall architecture of the lung tissue remained intact. |
T111 |
1160-1292 |
Sentence |
denotes |
However, a prominent amount of fibromyxoid or fibroblastic bodies was present in the alveoli with surrounding histiocytes (Fig. 2A . |
T112 |
1293-1366 |
Sentence |
denotes |
The extent of involved lung tissue was estimated at around 25% (Table 2). |
T113 |
1367-1451 |
Sentence |
denotes |
No remnants of hyaline membranes or prominent alveolar fibrinous exudate were found. |
T114 |
1452-1590 |
Sentence |
denotes |
Microthrombi in small blood vessels of the alveolar septa were seen, as well as an organizing thrombus in a larger sized vessel (Fig. 2E). |
T115 |
1591-1705 |
Sentence |
denotes |
The histologic findings in this case point towards an epithelial, and vascular phenotype of a SARS-CoV2 infection. |
T116 |
1706-1746 |
Sentence |
denotes |
No fungi were present in de PAS-D stain. |
T117 |
1747-1817 |
Sentence |
denotes |
This histologic pattern is characteristic for an organizing pneumonia. |
T118 |
1818-1851 |
Sentence |
denotes |
Fig. 2 Microscopic lung findings. |
T119 |
1852-2474 |
Sentence |
denotes |
A, case 1: intra-alveolar fibroblastic bodies, consistent with organizing pneumonia, (H&E, 10×) B, case 2: loss of alveolar architecture with extensive fibrosis (H&E; 10×) C, case 3: inflammatory infiltrate with neutrophils and lymphocytes, note the hyaline membranes (arrows), suggestive for diffuse alveolar damage. (H&E, 20×) D, case 4: prominent fibrinous exudate in alveoli as seen in AFOP (H&E; 10×) E: thrombus in larger vessel (H&E, 5×) F: cytopathogenic changes in pneumocytes due to viral infection seen in all cases: hyperplasia, multinucleated giant cells (asterisks), intranuclear inclusion bodies (H&E, 40×). |