PMC:7335649 / 304-1262 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T5 0-190 Sentence denotes In a meta-analysis of 29 controlled trials with 11,306 participants, we showed that regular vitamin C intake of around 1 g/day did not prevent upper respiratory tract infections (URTIs) [4].
T6 191-328 Sentence denotes However, the same trials found that vitamin C shortened and alleviated URTIs that occurred during the period of vitamin C administration.
T7 329-411 Sentence denotes In adults the duration of infections was reduced by 8% and in children by 14% [4].
T8 412-594 Sentence denotes Given the low frequency and usually mild symptoms of URTIs, and the relatively small benefit, prophylactic daily vitamin C dosing does not seem worthwhile under normal circumstances.
T9 595-769 Sentence denotes However, noting that many URTIs are caused by endemic coronaviruses, there is no reason or evidence to assume that vitamin C would be completely ineffective against COVID-19.
T10 770-958 Sentence denotes Given that COVID-19 is often much more severe than ordinary URTIs, the above estimates might justify a regular increased daily intake of vitamin C while the prevalence of COVID-19 is high.