LitCovid-sentences  

PMC:7335494 / 85981-90672 JSONTXT 11 Projects

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Id Subject Object Predicate Lexical cue
T513 0-192 Sentence denotes The anti-inflammatory effects induced by polyphenols in human studies with dietary interventions and weight related outcomes are heterogeneous, as summarized from recent literature (Table 7 ).
T514 193-418 Sentence denotes Thus, in a clinical study with double-blind, randomized, cross-over design, the effect of a commercially available polyphenols rich extract was tested, the study including patients having more than two metabolic risk factors.
T515 419-575 Sentence denotes Results showed a reduction of MCP-1 and MIF, but not of other markers of CVD risk (CRP, IL-6, HDL, adiponectin and oxidized LDL) (Broekhuizen et al., 2011).
T516 576-740 Sentence denotes In a separate clinical study with cross-over design, overweight patients consumed a high-carbohydrate, moderate-fat meal supplemented with strawberry/placebo juice.
T517 741-942 Sentence denotes The anthocyanin supplementation blunted the postprandial inflammatory response (reduced CRP level) induced by the high fat diet and reduced the postprandial insulin response (Edirisinghe et al., 2011).
T518 943-1124 Sentence denotes Furthermore, a double-blind study focused on hypercholesterolemia subjects, receiving a purified anthocyanin mixture, resulted in a reduction of their CRP, sVCAM-1 and IL-1β levels.
T519 1125-1320 Sentence denotes Similar results were obtained for HepG2 and porcine iliac artery endothelial cells exposed to the same purified anthocyanin mixture (reduction of LPS-induced VCAM-1 secretion) (Zhu et al., 2013).
T520 1321-1401 Sentence denotes Patients with early atherosclerosis, received simple or EGCG-enriched olive oil.
T521 1402-1586 Sentence denotes Independent of EGCG addition, olive oil reduced inflammatory markers and endothelial dysfunction (sICAM, white blood cells, monocytes, lymphocytes and platelets) (Widmer et al., 2013).
T522 1587-1673 Sentence denotes Table 7 Clinical data regarding the efficacy of polyphenols on inflammatory phenomena.
T523 1674-1743 Sentence denotes Design Population Type of intervention Inflammatory outcome Reference
T524 1744-1859 Sentence denotes Randomised, double-blind, cross-over study 34 subjects with two or more metabolic risk factors 4-week intervention:
T525 1860-1978 Sentence denotes 500 mg polyphenols/day vs. placebo ↓MCP-1 and MIF, unchanged levels of HDL, adiponectin, CRP Broekhuizen et al. (2011)
T526 1979-2165 Sentence denotes Cross-over study 24 overweight adults high-carbohydrate, moderate-fat meal together with a strawberry beverage (SB) or placebo SB:↓ CRP and postprandial insulin Edirisinghe et al. (2011)
T527 2166-2246 Sentence denotes Randomised, double-blind 150 hypercholesterolemic subjects 24-week intervention:
T528 2247-2321 Sentence denotes 640 mg purified Anthocyanin/day ↓ CRP, sVCAM-1 and IL-1β Zhu et al. (2013)
T529 2322-2408 Sentence denotes Randomised, double-blind 52 patients with early atherosclerosis, 4-month intervention:
T530 2409-2550 Sentence denotes 30 mL olive oil or 30 ml of EGCG-supplemented olive oil ↓ sICAM, white blood cells, monocytes, lymphocytes and platelets Widmer et al. (2013)
T531 2551-2848 Sentence denotes Single-centre, randomised, two-arm, double-blinded, placebo-controlled study 36 pre-hypertension patients, randomized to control or treatment groups 6-week intervention: grape seed extract, 150 mgx2/day ↓BP (SBP, DBP)↑ fasting insulin and insulin sensitivityNo change of sICAM-1 Park et al. (2016)
T532 2849-2945 Sentence denotes Single blinded crossover trial 38 patients with untreated mild hypertension 8-week intervention:
T533 2946-3056 Sentence denotes 300 mL/day cold-pressed 100% chokeberry juice and 3 g/day chokeberry powder ↓IL-10 and TNF-α Loo et al. (2016)
T534 3057-3286 Sentence denotes Randomized, double-blind, placebo-controlled clinical trial 50 hyperlipidemic patients 4-week intervention: V. arctostaphylos fruit extract x2/day no effects on HDL and CRP↓ total cholesterol, LDL-C, TG, MDA Soltani et al. (2014)
T535 3287-3365 Sentence denotes Placebo controlled study 20 study subjects and 19 placebo 4-week intervention:
T536 3366-3521 Sentence denotes 361 mg polyphenols and 120 mg vitamin C x2/day No significant effects on apolipoproteins, adiponectin, CRP, ICAM-1, E-Selectin or t-PA Mullan et al. (2016)
T537 3522-3586 Sentence denotes Placebo controlled study 16 trained cyclists 7-day intervention:
T538 3587-3696 Sentence denotes 30 mL of Montmorency tart cherry concentrate x 2/day ↓lipid hydroperoxides, IL-6 and hsCRP Bell et al. (2014)
T539 3697-3790 Sentence denotes Double-blind crossover study 49 healthy male subjects with APOE genotype 8-week intervention:
T540 3791-3964 Sentence denotes 150 mg/day quercetin or placebo (3 phases, three-week washout periods) ↓ waist circumference and postprandial SBP, moderately increased levels of TNFα Pfeuffer et al. (2013)
T541 3965-4138 Sentence denotes Randomised, double-blind, placebo-controlled, cross-over trial 18 healthy volunteers One-tine administration of 51 mg of oleuropeine ↓of IL8 production Lockyer et al. (2015)
T542 4139-4527 Sentence denotes Cross-sectional study 1997 females Frequency questionnaires assessment of total intake of flavonoids Higher anthocyanin and flavone intake were associated with significantly lower peripheral insulin resistanceHigher anthocyanin intake was also associated with lower CRP concentrationsHigher anthocyanin-rich intake was associated with lower insulin and inflammation Jennings et al. (2014)
T543 4528-4691 Sentence denotes Randomized, controlled dietary study 27 subjects with metabolic syndrome 400 g fresh bilberries/days vs. control diet ↓ CRP, IL-6, IL-12, Kolehmainen et al. (2012)