Id |
Subject |
Object |
Predicate |
Lexical cue |
T108 |
0-127 |
Sentence |
denotes |
Table 1 Clinical studies regarding the effect of high fibre intake on inflammatory markers in obesity and associated pathology. |
T109 |
128-184 |
Sentence |
denotes |
Design Population Dietary intervention Outcome Reference |
T110 |
185-496 |
Sentence |
denotes |
Randomized cross-over trial 50 Danish subjects with high risk of metabolic syndrome two 8-week periods of whole grain intake (179 ± 50 g/day)/refined grain (maximum 13 ± 10 g/day of whole grain), divided by a washout period of ≥6 weeks. ↓ body weight, serum inflammatory markers (IL-6, CRP) Roager et al. (2019) |
T111 |
497-780 |
Sentence |
denotes |
Double-blind, crossover, placebo-controlled, randomized study 45 metabolic syndrome patients risk factors galactooligosaccharide mixture intervention to increase dietary fibre content, with a 4-wk wash-out period between interventions ↓ faecal calprotectin, CRP Vulevic et al. (2013) |
T112 |
781-1078 |
Sentence |
denotes |
Randomized controlled trial 143 individuals with metabolic syndrome 12 weeks of rye and whole wheat was compared with a diet containing the equivalent amount of refined cereal foods no significant effects on the expression of inflammatory markers' genes or insulin sensitivity Giacco et al. (2013) |
T113 |
1079-1293 |
Sentence |
denotes |
Randomized crossover study 19 adults with metabolic syndrome 4-week of arabinoxylan and resistant starch enriched diet versus Western-style, low-fibre diet ↓ faecal calprotectin, IL-23A and NF-κB Hald et al. (2016) |
T114 |
1294-1496 |
Sentence |
denotes |
Crossover intervention study 25 hypercholesterolemic subjects 5-week intervention using low fibre and high fibre diet, separated by a 3-week washout. ↓ CRP and fibrinogen Johansson-Persson et al. (2014) |
T115 |
1497-1720 |
Sentence |
denotes |
Randomized controlled trial 68 overweight with prediabetes 12 weeks of 45 g/d of high-amylose maize (RS2) versus an isocaloric amount of amylopectin (control) ↓ TNF-α, no change in insulin sensitivity Peterson et al. (2018) |
T116 |
1721-2029 |
Sentence |
denotes |
Randomized controlled trial 166 subjects with features of metabolic syndrome 4-week using healthy diet (fruits and vegetables, berries, whole-grain products, rapeseed oil, three fish meals per week) compared to an regular Nordic diet Control diet: ↑ IL-1 Ra (versus healthy diet group) Uusitupa et al. (2013) |
T117 |
2030-2406 |
Sentence |
denotes |
Crossover study 10 healthy subjects Subjects received either 910calorie high- carbohydrate/high-fat meal or a standard meal according to American Heart Association (based on fruit and fibre) during the first visit and the other meal during the second visit ↑ oxidative stress (bloodlevels of TBARS, LPS, FFA) and proinflammatory markers (TNFα, and IL-1β) Dandona et al. (2015) |
T118 |
2407-2575 |
Sentence |
denotes |
Randomized controlled trial 28 T2DM patients Subjects received brown rice (n = 14) or white rice (n = 14) diet for 8 weeks ↓ CRP in brown rice group Kondo et al. (2017) |
T119 |
2576-2864 |
Sentence |
denotes |
Parallel design, dietary intervention trial 104 subjects with metabolic syndrome risk Subjects received Healthy Diet (n = 44), a whole-grain-enriched diet (n = 42) or a control (n = 45) diet, Healthy Diet group: ↓ E-selectinHealthy Diet and whole grain group: ↓ CRP de Mello et al. (2011) |
T120 |
2865-3179 |
Sentence |
denotes |
Cross-over, randomized, placebo-controlled, double-blind, study 12 overweight and obese subjects Subjects received 20 g/day of inulin (high-fermentable fibre) and cellulose (low-fermentable fibre) for 42 days IPE: ↓ IL-8 levels (versus cellulose)Inulin: no effect on the inflammatory markers Chambers et al. (2019) |
T121 |
3180-3435 |
Sentence |
denotes |
Crossover clinical study 18 subjects at low-to-moderate cardiometabolic risk Subjects received breakfast either rich in fibre, unsaturated fatty acids (unSFA) or saturated fatty acids (SFA) for 4 weeks SFA: ↑ IL-1β unSFA: ↓IL-6 Monfort-Pires et al. (2018) |
T122 |
3436-3694 |
Sentence |
denotes |
Interventional diet study 21 overweight/obese children Subjects were placed on a regimen of low-fat, high-fibre diet and daily exercise for 2 weeks ↓ PAI-1, TNF-α, IL-6, IL-8, resistin, insulin, amylin, leptin, and IL-1ra↑ adiponectin Izadpanah et al. (2012) |
T123 |
3695-3879 |
Sentence |
denotes |
Randomized, placebo-controlled study 31 hemodialysis patients Patients received either resistant starch or placebo supplementation, for 4 weeks ↓ IL-6 and TBARS Esgalhado et al. (2018) |
T124 |
3880-4100 |
Sentence |
denotes |
Randomized controlled clinical trial 55 women with T2DM Subjects received 10 g resistant dextrin/day or a similar amount of maltodextrin for 8 weeks ↓ IL-6, TNF-α and MDA↑ Insulin sensitivity Aliasgharzadeh et al. (2015) |
T125 |
4101-4341 |
Sentence |
denotes |
Randomized cross-over double-blind placebo-controlled trial 17 obese knee osteoarthritis patients Patients received freeze-dried strawberries or placebo for 2 periods of 12 weeks with 2 weeks of wash-out ↓ TNF-α and 4-HNE Basu et al. (2018) |
T126 |
4342-4529 |
Sentence |
denotes |
Randomized study 59 T2DM patients Patients received metformin, acarbose and either a high fibre or a low fibre diet intervention for 8 weeks Low fibre group: ↓ IL-18 Nowotny et al. (2015) |
T127 |
4530-4694 |
Sentence |
denotes |
Crossover study 33 healthy, middle-aged adults Patients received either high or low in in wholegrain intervention for 6-week periods, separated by a 4-week washout. |
T128 |
4695-4768 |
Sentence |
denotes |
Whole grain: a slight decrease of IL-10 and CRP Ampatzoglou et al. (2016) |
T129 |
4769-4991 |
Sentence |
denotes |
Observational study 8 subjects with impaired fasting glucose subjects received (1) high-fibre formula; (2) high-monounsaturated fatty acid formula or (3) control formula High fibre group: ↓ NF-κB in PBMCs Kim et al. (2013) |
T130 |
4992-5183 |
Sentence |
denotes |
Randomized controlled clinical trial 60 females with T2DM Patients received 10 g/d resistant starch or placebo for 8 weeks, respectively ↓TNF-α, no effect on IL-6 or CRP Gargari et al. (2015) |
T131 |
5184-5397 |
Sentence |
denotes |
Crossover clinical trial 80 overweight subjects Subjects received two isocaloric breakfast interventions -one rich in saturated fat and one in unsaturated fatty acids and fibres for 4 weeks with a 2-weeks washout. |
T132 |
5398-5455 |
Sentence |
denotes |
Fibre group: ↓ IF-γ and TNF-α Monfort-Pires et al. (2018) |
T133 |
5456-5615 |
Sentence |
denotes |
Observational study 49 T2DM females Patients received either 10 g/day inulin or maltodextrin/day for 8 weeks Inulin: ↓CRP, TNF-α and LPS Dehghan et al. (2014a) |
T134 |
5616-5866 |
Sentence |
denotes |
Randomized controlled clinical trial 52 overweight/obese women with T2DM Patients received either 10 g/d of oligofructose-enriched inulin or maltodextrin (control) for 8 weeks oligofructose-enriched-Inulin: ↓ CRP, TNF-α and LPS Dehghan et al. (2014b) |
T135 |
5867-6107 |
Sentence |
denotes |
Randomized crossover clinical trial 44 overweight/obese girls 8–15 years old Subjects received either whole-grain or control for 2 periods of 6 weeks with 4-week washout period Whole grain: ↓ CRP, ICAM-1 and leptin Hajihashemi et al. (2014) |