PMC:7321036 / 38058-39453 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T247 81-127 Sentence denotes (A) Diagram of the p38/MAPK signaling pathway.
T248 128-193 Sentence denotes (B) Kinase activity analysis for kinases in the p38/MAPK pathway.
T249 194-338 Sentence denotes (C) Western blot analysis of phosphorylated p38/MAPK signaling components in mock- and SARS-CoV-2-infected ACE2-A549 cells 24 h after infection.
T250 339-447 Sentence denotes (D) Log2 fold change profiles of indicated p38/MAPK substrates during SARS-CoV-2 infection in Vero E6 cells.
T251 448-653 Sentence denotes (E) Transcription factor activity analysis of SARS-CoV-2-infected A549, Calu-3, and NHBE cells, comparing p38/MAPK transcription factors with transcription factors not associated with the p38/MAPK pathway.
T252 654-671 Sentence denotes Statistical test:
T253 672-690 Sentence denotes Mann-Whitney test.
T254 691-883 Sentence denotes (F) qRT-PCR analysis of the indicated mRNA from ACE2-A549 cells pre-treated with the p38 inhibitor SB203580 at the indicated concentrations for 1 h prior to infection with SARS-CoV-2 for 24 h.
T255 884-901 Sentence denotes Statistical test:
T256 902-919 Sentence denotes Student’s t test.
T257 920-947 Sentence denotes See also Figures S4 and S5.
T258 948-1162 Sentence denotes (G) Heatmap of Pearson’s correlation coefficients comparing SARS-CoV-2-infected Vero E6 phosphorylation profiles with profiles of cells with induced DNA damage and cells arrested at the indicated cell cycle stages.
T259 1163-1292 Sentence denotes (H) Log2 fold change profiles of the indicated cell cycle and DNA damage substrates during SARS-CoV-2 infection in Vero E6 cells.
T260 1293-1395 Sentence denotes (I) DNA content analysis of cells infected with SARS-CoV-2 for 24 h compared with mock-infected cells.