PMC:7321036 / 32244-33827 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T206 0-70 Sentence denotes Figure 5 Colocalization of CK2 and Viral Proteins at Actin Protrusions
T207 71-176 Sentence denotes (A) Pathway of regulated PHs and SARS-CoV-2 interaction partners involved in cytoskeletal reorganization.
T208 177-279 Sentence denotes Dashed lines indicate downregulation of activity, while solid lines indicate upregulation of activity.
T209 280-348 Sentence denotes (B) Regulation of individual kinase activity or PHs depicted in (A).
T210 349-481 Sentence denotes (C) Caco-2 cells infected with SARS-CoV-2 at an MOI of 0.1 for 24 h prior to immunostaining for F-actin and M protein, as indicated.
T211 482-628 Sentence denotes Shown is a confocal section revealing M protein localization along and to the tip of filopodia (left) and magnification of the dashed box (right).
T212 629-765 Sentence denotes (D) Dot plot quantification of the number and length of filopodia in untreated (mock) or infected Caco-2 cells for 24 h with SARS-CoV-2.
T213 766-850 Sentence denotes Filopodium length was measured from the cortical actin to the tip of the filopodium.
T214 851-875 Sentence denotes Error bars represent SD.
T215 876-917 Sentence denotes Statistical testing by Mann-Whitney test.
T216 918-1082 Sentence denotes (E) Caco-2 cells infected with SARS-CoV-2 at an MOI of 0.01 for 24 h prior to immunostaining for F-actin, N protein, and casein kinase II (CK2) as indicated (left).
T217 1083-1151 Sentence denotes Shown is magnification of the dashed box as single channels (right).
T218 1152-1294 Sentence denotes (F) Magnification of the dashed box from (E) with quantification of colocalization between CK2 and N protein throughout infected Caco-2 cells.
T219 1295-1377 Sentence denotes Displayed is the proportion of N protein-positive particles colocalizing with CK2.
T220 1378-1402 Sentence denotes Error bars represent SD.
T221 1403-1563 Sentence denotes (G and H) Scanning electron microscopy (G) and transmission electron microscopy (H) images of SARS-CoV-2 budding from Vero E6 cell filopodia (black arrow in H).
T222 1564-1583 Sentence denotes See also Figure S3.