Id |
Subject |
Object |
Predicate |
Lexical cue |
T34 |
0-148 |
Sentence |
denotes |
Finally, accumulating evidence indicates that prematurity might also be associated with higher ACE2 activity and/or expression (South et al., 2018). |
T35 |
149-317 |
Sentence |
denotes |
ACE-2 is known to be directly involved in SARS-CoV-2 cell-binding, representing the main host cell receptor for all human pathogenic coronaviruses including SARS-CoV-2. |
T36 |
318-438 |
Sentence |
denotes |
Thus, the higher ACE2 activity/expression in the prematurely born individuals might result in greater COVID-19 severity. |
T37 |
439-703 |
Sentence |
denotes |
One also has to bear in mind that the prematurity-related higher ACE2 activity might be additionally heightened by potential hypertension or diabetes drug therapies which often include ACE inhibitors and/or angiotensin II receptor blockers, both upregulating ACE2. |