| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T70 |
0-124 |
Sentence |
denotes |
The spike (S) protein, which is projected outward on the surface of the virion is the very important pathogenic determinant. |
| T71 |
125-167 |
Sentence |
denotes |
The S protein has two subunits, S1 and S2. |
| T72 |
168-284 |
Sentence |
denotes |
The S1 binds on angiotensin-converting enzyme 2 (ACE2), the host cell receptor, and the S2 mediates membrane fusion. |
| T73 |
285-336 |
Sentence |
denotes |
The receptor-binding domain (RBD) of S1 binds ACE2. |
| T74 |
337-446 |
Sentence |
denotes |
The Cryo-electron microscopic structure of the spike protein of SARS-CoV-2 has been determined at 3.5°A [15]. |
| T75 |
447-542 |
Sentence |
denotes |
The study showed SARS-CoV-2 S protein has higher affinity to ACE2 compared to that of SARS-CoV. |
| T76 |
543-709 |
Sentence |
denotes |
The mutation at 614 position in the S protein of SARS-CoV-2 from aspartic acid to glycine (D614G) was identified to reduce S1 shedding and increases infectivity [17]. |
| T77 |
710-882 |
Sentence |
denotes |
The sequence analysis showed that the G614 genotype has steadily increased from March to May 2020, indicating a transmission advantage of the virus with G614 mutation [17]. |
