| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T20 |
0-24 |
Sentence |
denotes |
Context and Significance |
| T21 |
25-104 |
Sentence |
denotes |
The COVID-19 pandemic presents an unprecedented threat to global public health. |
| T22 |
105-245 |
Sentence |
denotes |
Systematic analyses of metabolic alterations during COVID-19 pathogenesis will uncover candidate pathways implicated in disease progression. |
| T23 |
246-555 |
Sentence |
denotes |
Here, using a combination of targeted and untargeted tandem mass spectrometry to profile the plasma lipidome and metabolome in COVID-19 patients and healthy controls, Song et al. revealed that the plasma lipidome of COVID-19 bears resemblance to that of monosialodihexosyl ganglioside (GM3)-enriched exosomes. |
| T24 |
556-746 |
Sentence |
denotes |
They validated observations made based on plasma by analyzing the lipidome of isolated exosomes and showed that GM3-enriched exosomes are correlated positively with the severity of COVID-19. |
| T25 |
747-905 |
Sentence |
denotes |
These results also confer a resource that can be mined to propel future mechanistic investigation of metabolic dysregulation underlying COVID-19 pathogenesis. |
