| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-86 |
Sentence |
denotes |
Omics-Driven Systems Interrogation of Metabolic Dysregulation in COVID-19 Pathogenesis |
| T2 |
88-96 |
Sentence |
denotes |
Abstract |
| T3 |
97-104 |
Sentence |
denotes |
Summary |
| T4 |
105-211 |
Sentence |
denotes |
The coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented threat to global public health. |
| T5 |
212-413 |
Sentence |
denotes |
Herein, we utilized a combination of targeted and untargeted tandem mass spectrometry to analyze the plasma lipidome and metabolome in mild, moderate, and severe COVID-19 patients and healthy controls. |
| T6 |
414-527 |
Sentence |
denotes |
A panel of 10 plasma metabolites effectively distinguished COVID-19 patients from healthy controls (AUC = 0.975). |
| T7 |
528-720 |
Sentence |
denotes |
Plasma lipidome of COVID-19 resembled that of monosialodihexosyl ganglioside (GM3)-enriched exosomes, with enhanced levels of sphingomyelins (SMs) and GM3s, and reduced diacylglycerols (DAGs). |
