Id |
Subject |
Object |
Predicate |
Lexical cue |
T15 |
0-581 |
Sentence |
denotes |
Through millions of years of evolution, viruses have gained a variety of molecular mechanisms for entry into cells; long-term survival within cells; and activation, inhibition, or modification of the host defense mechanisms at all levels.1 Their ability to transfer genes with high efficiency inspired the development of noninfectious recombinant viral vectors for gene-therapy applications, beginning in 1990.2−4 Efforts were then underway to improve the safety of viral vectors, including developing nonviral drug-delivery systems inspired by the natural capabilities of viruses. |
T16 |
582-742 |
Sentence |
denotes |
Researchers in the field of nanomedicine have designed a variety of nanosystems that can mimic the gene-transfer capacity and high infectivity of viral vectors. |
T17 |
743-1102 |
Sentence |
denotes |
By learning the molecular mechanisms behind these vectors, nanomedicine and biomedical researchers have developed delivery systems used in different fields, including cancer therapy and regenerative medicine.5,6 However, nanotechnology is not only inspired by virology to develop novel delivery tools but also at the forefront in combatting dangerous viruses. |