Id |
Subject |
Object |
Predicate |
Lexical cue |
T5 |
3-141 |
Sentence |
denotes |
The discovery of potent and specific antiviral inhibitors and/or vaccines to fight these massive outbreaks is an urgent research priority. |
T6 |
142-323 |
Sentence |
denotes |
Enzymes involved in the capping pathway of viruses and more specifically RNA N7- or 2′O-methyltransferases (MTases) are now admitted as potential targets for antiviral chemotherapy. |
T7 |
324-468 |
Sentence |
denotes |
We designed bisubstrate inhibitors by mimicking the transition state of the 2′-O-methylation of the cap RNA in order to block viral 2′-O MTases. |