PMC:7291971 / 1788-2193 JSONTXT 8 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T15 0-76 Sentence denotes • Bisubstrates as mimics of RNA 2′-O-methylation transition state with SAM.
T16 77-163 Sentence denotes • 16 dinucleosides with two adenosines joined by various nitrogen-containing linkers.
T17 164-246 Sentence denotes • Bisubstrate compounds were barely active against viral 2′-O-methyltransferases.
T18 247-334 Sentence denotes • Discovery of a potent and specific inhibitor of SARS-CoV nsp14 N7-methyltransferase.
T19 335-405 Sentence denotes • Molecular docking and biophysical assays corroborated observed SAR.