Id |
Subject |
Object |
Predicate |
Lexical cue |
T15 |
0-76 |
Sentence |
denotes |
• Bisubstrates as mimics of RNA 2′-O-methylation transition state with SAM. |
T16 |
77-163 |
Sentence |
denotes |
• 16 dinucleosides with two adenosines joined by various nitrogen-containing linkers. |
T17 |
164-246 |
Sentence |
denotes |
• Bisubstrate compounds were barely active against viral 2′-O-methyltransferases. |
T18 |
247-334 |
Sentence |
denotes |
• Discovery of a potent and specific inhibitor of SARS-CoV nsp14 N7-methyltransferase. |
T19 |
335-405 |
Sentence |
denotes |
• Molecular docking and biophysical assays corroborated observed SAR. |