Id |
Subject |
Object |
Predicate |
Lexical cue |
T104 |
0-125 |
Sentence |
denotes |
Scheme 4 depicts the synthesis of the adenine dinucleosides 14–16 from the intermediate NH-linked dinucleoside 20 (Scheme 2). |
T105 |
126-254 |
Sentence |
denotes |
The reaction of 4-chlorobenzenesulfonyl chloride with 20 in the presence of NEt3 [31,32] followed by a TFA treatment yielded 14. |
T106 |
255-483 |
Sentence |
denotes |
The treatment of 20 with 4-chloro-3-nitrobenzaldehyde or 4-chlorobenzaldehyde and sodium triacetoxyborohydride, followed by the removal of protective groups in acidic conditions resulted in dinucleosides 15 and 16, respectively. |
T107 |
484-600 |
Sentence |
denotes |
It is noteworthy that this reductive amination conducted at 40 °C increased the yields to 71% and 81%, respectively. |