PMC:7289100 / 9356-10987 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T57 0-53 Sentence denotes 5 Miller Fisher syndrome (MFS) secondary to COVID-19
T58 54-202 Sentence denotes MFS is a rare, acquired disease that is considered to be a mild variant of Guillain-Barré syndrome, and is observed in about 5% of all cases of GBS.
T59 203-276 Sentence denotes It is characterized by a triad of ataxia, areflexia, and ophthalmoplegia.
T60 277-339 Sentence denotes Acute onset of external ophthalmoplegia is a cardinal feature.
T61 340-407 Sentence denotes Ataxia tends to be out of proportion to the degree of sensory loss.
T62 408-489 Sentence denotes Patients may also have mild limb weakness, ptosis, facial palsy, or bulbar palsy.
T63 490-567 Sentence denotes Occasionally generalized muscle weakness and respiratory failure may develop.
T64 568-659 Sentence denotes Patients have reduced or absent sensory nerve action potentials and absent tibial H reflex.
T65 660-714 Sentence denotes Like GBS, symptoms may be preceded by a viral illness.
T66 715-852 Sentence denotes The majority of individuals with MFS have unique antibodies that characterize the disorder, which are Anti-GQ1b and anti-GD1b antibodies.
T67 853-1039 Sentence denotes Dense concentrations of GQ1b ganglioside are found in the oculomotor, trochlear, and abducens nerves, which may explain the relationship between anti-GQ1b antibodies and ophthalmoplegia.
T68 1040-1145 Sentence denotes Treatment for MFS is identical to treatment for GBS: intravenous immunoglobulin (IVIG) or plasmapheresis.
T69 1146-1286 Sentence denotes A group from Spain reported of two patients infected with SARS-CoV-2 who acutely presented with MFS and polyneuritis cranialis respectively.
T70 1287-1350 Sentence denotes Both patients presented with the typical neurological symptoms.
T71 1351-1497 Sentence denotes One of the two patients was found to be positive for anti-GD1b-IgG antibodies and was treated with IVIG and the second patient with acetaminophen.
T72 1498-1631 Sentence denotes Two weeks later, both patients made a complete neurological recovery, except for residual anosmia and ageusia in the first case [39].