Id |
Subject |
Object |
Predicate |
Lexical cue |
T57 |
0-53 |
Sentence |
denotes |
5 Miller Fisher syndrome (MFS) secondary to COVID-19 |
T58 |
54-202 |
Sentence |
denotes |
MFS is a rare, acquired disease that is considered to be a mild variant of Guillain-Barré syndrome, and is observed in about 5% of all cases of GBS. |
T59 |
203-276 |
Sentence |
denotes |
It is characterized by a triad of ataxia, areflexia, and ophthalmoplegia. |
T60 |
277-339 |
Sentence |
denotes |
Acute onset of external ophthalmoplegia is a cardinal feature. |
T61 |
340-407 |
Sentence |
denotes |
Ataxia tends to be out of proportion to the degree of sensory loss. |
T62 |
408-489 |
Sentence |
denotes |
Patients may also have mild limb weakness, ptosis, facial palsy, or bulbar palsy. |
T63 |
490-567 |
Sentence |
denotes |
Occasionally generalized muscle weakness and respiratory failure may develop. |
T64 |
568-659 |
Sentence |
denotes |
Patients have reduced or absent sensory nerve action potentials and absent tibial H reflex. |
T65 |
660-714 |
Sentence |
denotes |
Like GBS, symptoms may be preceded by a viral illness. |
T66 |
715-852 |
Sentence |
denotes |
The majority of individuals with MFS have unique antibodies that characterize the disorder, which are Anti-GQ1b and anti-GD1b antibodies. |
T67 |
853-1039 |
Sentence |
denotes |
Dense concentrations of GQ1b ganglioside are found in the oculomotor, trochlear, and abducens nerves, which may explain the relationship between anti-GQ1b antibodies and ophthalmoplegia. |
T68 |
1040-1145 |
Sentence |
denotes |
Treatment for MFS is identical to treatment for GBS: intravenous immunoglobulin (IVIG) or plasmapheresis. |
T69 |
1146-1286 |
Sentence |
denotes |
A group from Spain reported of two patients infected with SARS-CoV-2 who acutely presented with MFS and polyneuritis cranialis respectively. |
T70 |
1287-1350 |
Sentence |
denotes |
Both patients presented with the typical neurological symptoms. |
T71 |
1351-1497 |
Sentence |
denotes |
One of the two patients was found to be positive for anti-GD1b-IgG antibodies and was treated with IVIG and the second patient with acetaminophen. |
T72 |
1498-1631 |
Sentence |
denotes |
Two weeks later, both patients made a complete neurological recovery, except for residual anosmia and ageusia in the first case [39]. |